recreational drugs Flashcards

1
Q

what is an agonist drug?

A

a drug that activates the synaptic receptor sites

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2
Q

what is an antagonist drug?

A

1) a drug that does not activate the synaptic receptor sites

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3
Q

what is does the reuptake inhibitor do?

A

blocks the reuptake of the neurotransmitters so more neutransmitters remain in the synpase, increases its action

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4
Q

what does the reward pathway involve?

A

the reward pathway involves activities that lead to an elevated level of dopamine and alleviates rhythms in the brain’s reward system

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5
Q

how does the reward system link to drug taking?

A

1) neurotransmitters are released into the mesolymbic pathway when you experience pleasure
2) different parts of the pathway have dopamine receptors that causes you to take that drug again

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6
Q

what makes up the mesolymbic pathway?

A

1) the hippocampus
2) the amygala
3) the nucleus accumbens

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7
Q

what does the nucleus accumbens do?

A

controls motor functions

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8
Q

what are the short term effects on cocaine?

A
  • increased behaviour and alertness
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9
Q

what are the long term effects of cocaine?

A
  • decreased serotonin
  • decreased dopamine
  • decreased need to eat and sleep
  • hypersensitivity
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10
Q

how does heroin impact neurotransmitters?

A
  • increases the amount of dopamine in the reward pathways in the brain
  • boosts the activation of dopaminergic synapses
  • the wearing off of dopamine leads to dysphoria
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11
Q

how does cocaine impact neurotransmitters?

A
  • exaggerates changes caused by noradrenaline and dopamine
  • increases alertness and causes euphoria
  • blocks the reuptake of dopamine in the presynaptic neuron so more dopamine remains in the synapse
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12
Q

what are the short term effects of heroin?

A
  • feeling of warmth
  • reduction of pain
  • slows down mental functions, breathing and heart rate
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13
Q

what are the long term efffect of heroin?

A
  • physical and psychological dependence
  • withdrawal symptoms as the brain adapts to the heroin
  • less endorphine is being produced = addiction
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14
Q

how does amphetamine impact neurotransmitters?

A
  • increases the levels of noradrenaline and dopamine by reversing the reuptake process in the synaptic gap
  • reduces the action of glutamine
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15
Q

what are the short term effects of amphetamine?

A
  • increased heart rate and blood pressure
  • reduced fatigue and feelings of happiness
  • decreased appetite
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16
Q

what are the long term effects of amphetamine?

A
  • insomnia
  • psychosis
  • depression like state
  • damaged dopamine receptors due to overstimulation = increased use of the drug = addiction
17
Q

how do people that take amphetamine become addicted?

A

because of damaged dopamine receptors, people would take MORE amphetamine as dopamine is required to stimulate the neuron to a normal level