recreational drugs Flashcards
(14 cards)
what is an agonist drug?
a drug that activates the synaptic receptor sites
what is an antagonist drug?
1) a drug that does not activate the synaptic receptor sites
what is does the reuptake inhibitor do?
blocks the reuptake of the neurotransmitters so more neutransmitters remain in the synpase, increases its action
what does the reward pathway involve?
the reward pathway involves activities that lead to an elevated level of dopamine and alleviates rhythms in the brain’s reward system
how does the reward system link to drug taking?
1) neurotransmitters are released into the mesolymbic pathway when you experience pleasure
2) different parts of the pathway have dopamine receptors that causes you to take that drug again
what makes up the mesolymbic pathway?
1) the hippocampus
2) the amygala
3) the nucleus accumbens
what does the nucleus accumbens do?
controls motor functions
how does heroin impact neurotransmitters?
- increases the amount of dopamine in the reward pathways in the brain
- boosts the activation of dopaminergic synapses
- the wearing off of dopamine leads to dysphoria
what are the short term effects of heroin?
- feeling of warmth
- reduction of pain
- slows down mental functions, breathing and heart rate
what are the long term efffect of heroin?
- physical and psychological dependence
- withdrawal symptoms as the brain adapts to the heroin
- less endorphine is being produced = addiction
how does amphetamine impact neurotransmitters?
- increases the levels of noradrenaline and dopamine by reversing the reuptake process in the synaptic gap
- reduces the action of glutamine
what are the short term effects of amphetamine?
- increased heart rate and blood pressure
- reduced fatigue and feelings of happiness
- decreased appetite
what are the long term effects of amphetamine?
- insomnia
- psychosis
- depression like state
- damaged dopamine receptors due to overstimulation = increased use of the drug = addiction
how do people that take amphetamine become addicted?
because of damaged dopamine receptors, people would take MORE amphetamine as dopamine is required to stimulate the neuron to a normal level