Rejection Flashcards
(3 cards)
0
Q
Early acute rejection
A
1 week to 10 days
T cell mediated - recipient T cells react to antigen present on donor vascular endothelium and dendritic cells with release of IL2
vascular response - mediated by antibody, noted by IgG and IgM antibodies bound to donor endothelium
1
Q
Hyper acute rejection?
A
Pre formed circulating antibodies react with MHC class 1 antigens on transplanted kidney
2
Q
Acute late rejection
A
11 days to 6 weeks
Florid antibody and complement mediated vascular damage
