Relative energy deficiencies in sports (RED-S) Flashcards

(28 cards)

1
Q

What is Relative Energy Deficiency in Sport (RED-S)?

A

RED-S is a syndrome of impaired physiological and/or psychological functioning experienced by female and male athletes that is caused by exposure to problematic (prolonged and/or severe) Low Energy Availability (LEA). It was formerly known as the Female Athlete Triad but the name was changed to be inclusive of men.

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2
Q

What is the underlying factor in RED-S?

A

Low energy availability is the underlying factor in the RED-S syndrome

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3
Q

Define energy balance in the context of RED-S.

A

Energy balance = Energy Intake (EI) – Energy Expenditure (EO)

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4
Q

What happens when an athlete is in negative energy balance for an extended period?

A

When in negative energy balance for weeks to months, athletes will exhibit signs/symptoms of RED-S

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5
Q

What are some detrimental outcomes of RED-S?

A

Detrimental outcomes of RED-S include, but are not limited to, decreases in:
* Energy metabolism
* Reproductive function
* Musculoskeletal health
* Immunity
* Glycogen synthesis
* Cardiovascular health
* Haematological health

These can all individually and synergistically lead to impaired well-being, increased injury risk, and decreased sports performance.

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6
Q

Can RED-S be related to disordered eating?

A

Yes, RED-S may be a sign of disordered eating.

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7
Q

Describe the spectrum of disordered eating.

A

Disordered eating is a continuum that ranges from “healthy dieting” to extreme weight loss and can include clinical eating disorders.

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8
Q

How common is disordered eating among athletes?

A

Disordered eating affects up to 62% of female athletes and 33% of male athletes.

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9
Q

Is RED-S the same as an eating disorder?

A

No, RED-S is not an eating disorder, though it can be a sign of one. There can be an unhealthy relationship with food involved.

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10
Q

What are the diagnostic manuals for feeding and eating disorders?

A

For more information on feeding and eating disorders and definitions, see the International Classification of Diseases (ICD-10) and the Diagnostic and Statistical Manual of Mental Disorders (DSM; 2013).

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11
Q

What are the key diagnostic criteria for Anorexia Nervosa related to energy availability?

A

Key criteria for Anorexia Nervosa include:
* Refusal to maintain body weight for age & height (e.g., BMI <17.5 or <85% of expected weight); failure to gain weight during growth
* Intense fear of gaining weight or fat
* Disturbed body image or denial of seriousness of current low body weight
* Amenorrhea

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12
Q

What are the key diagnostic criteria for Bulimia Nervosa related to energy availability?

A

Key criteria for Bulimia Nervosa include:
* Recurrent episodes of binge eating: Eating a larger amount of food in a discrete time with a sense of lack of control
* Recurrent, inappropriate, compensatory behavior to prevent weight gain
* Binge eating and inappropriate compensatory behaviors occur at least twice a week for 3 months
* Self-evaluation influenced by body image
* May occur with or without Anorexia Nervosa

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13
Q

Define menarche, eumenorrhea, oligomenorrhea, and amenorrhea.

A
  • Menarche: first menstrual cycle (12.5 years average)
  • Eumenorrhea: menstrual cycles at intervals near the median interval for young adult women (28 days; range 21-35)
  • Oligomenorrhea: menstrual cycles at intervals longer than 35 days (or infrequent menstrual cycle; 3-6/yr)
  • Amenorrhea: Absence of menstrual cycle lasting >3 months.
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14
Q

Differentiate between primary and secondary amenorrhea.

A
  • Primary Amenorrhea: delayed menarche (15 yr)
  • Secondary Amenorrhea: occurs after menarche.
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15
Q

Define luteal suppression and anovulation.

A
  • Luteal suppression: a menstrual cycle with a luteal phase shorter than 11 days or with a low concentration of progesterone.
  • Anovulation: a menstrual cycle without ovulation
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16
Q

What is the estimated prevalence of primary amenorrhea in the general population and in some sports?

A

Primary amenorrhea has been estimated at ~7% overall, with 22% in cheerleading, diving, and gymnastics.

17
Q

What is the estimated prevalence of secondary amenorrhea in the general female population and in certain athletic groups?

A

Secondary amenorrhea has been estimated to be 2-5% in women, and as high as 69% in dancers and 65% in long-distance runners.

18
Q

How quickly can menstrual dysfunction occur due to low energy availability? How long can recovery take?

A

Menstrual dysfunction can occur in as little as 1 month of low energy availability but more likely 2-3 months. It takes 3-6 months to recover after improvement in energy availability. For some girls, it may take double the amount of time to recover.

19
Q

What are some important questions to consider regarding menstrual dysfunction in athletes?

A

Important questions include: What is the cause? (e.g., low energy intake, high energy expenditure leading to functional hypothalamic amenorrhea). It’s important to be aware if the absence of a period is due to an underlying condition like PCOS or something else.

20
Q

Explain the relationship between LH pulsatility and menstrual dysfunction.

A

Disruption of LH pulsatility is a cause of menstrual dysfunction. Low Energy Availability (LEA) reduced LH pulsatility by ~60%.

21
Q

What is the misconception some athletes, coaches, and trainers have about amenorrhea?

A

Some consider amenorrhea a benign consequence of training, an indicator of good training, and that body fat levels are at an optimal level for performance - this is a serious misconception.

22
Q

What are some potential causes of menstrual problems in athletes?

A

Causes of menstrual problems in athletes are multifactorial (physiological and psychological), and insufficient energy availability may result in menstrual problems.

23
Q

Define low bone mineral density (osteopenia) and osteoporosis based on Z-scores.

A
  • Low Bone Mineral Density (BMD) (aka osteopenia): bone mineral density Z-score between -1.0 and -2.0.
  • Osteoporosis: bone mineral density Z-score < -2.0 with secondary risk factors for fracture (e.g., undernutrition, hypoestrogenism, prior fractures). A DEXA scan can reveal BMD.
24
Q

Why is estrogen important for bone health?

A

It influences bone metabolism by affecting cells like osteoblasts (bone-building) and osteoclasts (bone-resorbing).

25
What are the causes of low BMD in athletes related to RED-S?
Causes of low BMD in athletes related to low energy availability include: * Low IGF-1 (promotes bone health) * High Cortisol * Perhaps low intake of calcium * Menstrual dysfunction/Low Estrogen
26
How does menstrual history affect bone mineral density?
Menstrual history is a major determinant of BMD: late menarche, menstrual irregularities, or amenorrhea lead to reduced peak BMD, premature bone loss, or increased fracture risk
27
What are the consequences of undernutrition and hypoestrogenism on bone health?
* Undernutrition: Decreases the rate of bone formation. * Hypoestrogen: Increases the bone resorption rate. These can lead to an increased risk of stress fractures and an increased risk of osteoporosis
28
What are the key components of RED-S treatment?
Key components of RED-S treatment include: * Seek proper help! Especially if an eating disorder is suspected. Involve a multidisciplinary healthcare team. * Aim to make Energy Availability (EA) > 30 kcal/ kg of FFM (preferably 45 kcal/ kg of FFM). ◦Nutrition counseling to: * Increase dietary Calcium (Ca2+) to 1000-1300 mg/d * Increase Vitamin D to 400-800 IU/d * Ensure adequate protein intake (1.2-1.6 g/kg/day) * Consider resistance training (to boost muscle/bone). * Consider decreasing overall training by 10-20%. * Aim to increase body weight by 2-3%. * Prioritize addressing training volume.