Renal Applied Anatomy Flashcards
(28 cards)
Function of the kidney
Removal of waste products
What is the other major filter in human body?
Liver
Loop of Henle
Descending and Ascending limb
Main functions of Nephron
Filtration
Reabsorption /Passive
Secretion /Passive
Why do you need to go Pee more in the cold ?
Does it mean that Glomerular Filtration is purely dependent on blood pressure and perfusion?
Hydrostatic pressure pushes the fluid out and the osmotic/oncotic pressure is the fluid that keeps it inside
2 forces ?
Afferent Arteriole
Vasoconstriction decrease GFR
Efferent Arteriole
Vasoconstriction increases GFR
Proximal Convoluted Tubule
70% of Reabsorption
Active secretions of large molecules
Ion Pumps
Na reabsorbed (exchanged for H+)
The only area sugar is being absorbed is Glucose
The proximal convoluted tubule is the only region
Secretion
Organic acids and bases
Hydrogen ions (H+)
drugs /toxins
Acid-Base Balance Renal Compensation
CO2 + H2O <H2CO3<H2CO3-+H+
More H+ in blood -lower the pH
Respiratory or metabolic problem?
Loop of Henle
Collecting system
Some H+ secretion
ADH controlled H20 reabsorption
Distal Convoluted tubule
Secretion of ions into the filtrate K+
Ca reabsorption
Renal function assessment
GFR, eGFR, Creatinine Clearance
Urea and Creatinine
Urea and creatinine both freely at the glomerulus
Creatinine is not reabsorbed
Urea reabsorbed by tubules through regulation
U/Cr ratio can be used as an indicator of the likely cause of renal failure
Prerenal
Normal or post-renal
Renal
> 100 :1
40-100 : 1
<40 :1
20 years of patient presenting with HTN and Haematuria, Renal function is very abnormal, Blood test show
Nephritic syndrome
Caused by autoimmune
Nephritic Vs Nephrotic
