Renal Biopsy

Question 1

What are the indications for renal biopsy?

Answer 1

• Intrinsic/ Renal AKI (exclusion of pre/post renal)
• (but not diabetes + HTN)
• Nephrotic syndrome
• Haematuria and non-nephrotic range proteinuria without signficant rise in creatinine

Question 2

What are the most common causes of Nephrotic syndrome?

Answer 2

Mostt common primary

1. Minimal change disease
2. FSGS (Focal Segmenttal gloerulosclerosis)
3. Memranous GN

Systemic diseases
1. Diabetes
2. Amyloidosis

Question 3

What does hypercellularity on renal biopsy signify?

Answer 3

Usually glomerulanephritis results in hypercellulariy

Depending on location s different ares –> Mesangial cells? (cells bvetween capiliaries)
Endocapillary? Capillary Wall?

Bowmans space?= Crescents