renal cancer Flashcards
1
Q
benign types
A
oncocytoma
angiomyolipoma
2
Q
malignant
A
renal adenocarcinoma
mostly from proximal tubule
3
Q
presentation
A
incidental and asymptomatic
flank pain, mass, haematuria (10%)
abnormal LFTs?
anemia
anorexia
metastatic disease
4
Q
investigations
A
CT of abdomen and chest mandatory
U&Es
FBC
US- tumour or cyst
DMSA or MAG3 to assess contralateral kidney
5
Q
treatment
A
radical nephrectomy
always surgery
IN METASTASES- little effective treatment as RCC is radio and chemo resistant : multitargeted receptor tyrosine kinase inhibitors eg sunitinib, sorafenib or immunotherpay eg interferon alpha or interleukin 1
6
Q
prognosis
A
varies hugely depending on TNM stage - T1 95% 5 year survival but if metastasises only 1 year
