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Flashcards in Renal Disease Deck (133)
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1

Most common causes of CKD

diabetes and HTN

2

what measures are used to determine the severity of kidney disease

proteinuria and GFR

3

MOA of loop diuretics

inhibit the Na-K pump in the ascending loop of Henle -> less water reabsorbed

4

Long term use of loop diuretics effect on calcium

depletion of calcium (harmful to bone)

5

MOA of thiazide diuretics

inhibit the Na-Cl pump in the distal tubule

6

long term use of thiazide diuretics on calcium

increases calcium reabsorption - protective effect on bone

7

Aldosterone MOA

increase Na and water retention and decrease K in the distal tubule

8

Risk factors for DIKD

multiple nephrotoxic medications, baseline reduction in renal blood flow, large doses or frequent use of nephrotoxic medications, and increased age

9

common medications associated with DIKD

aminioglycosides, amphotericin B, cisplatin, colistimethate, cyclosporine, loop diuretics, NSAIDs, radiographic contrast dye, tacrolimus, and vancomycin

10

When is CrCl based estimations of kidney function limited

low or high muscle mass, obese, liver disease, pregnancy

11

GFR considered normal or high in CKD

90+ and kidney damage

12

GFR considered mild decrease in CKD

60-89 with kidney damage

13

GFR considered mild-moderate disease in CKD

45-59

14

GFR considered moderate-severe disease in CKD

30-44

15

GFR considered severe disease in CKD

15-29

16

GFR considered kidney failure in CKD

17

GFR category G1

90+ and kidney damage

18

GFR category G2

60-89 and kidney damage

19

GFR category G3a

45-49

20

GFR category G3b

30-44

21

GFR category G4

15-29

22

GFR category G5

23

CKD stage 1 GFR

90+ and kidney damage

24

CKD stage 2 GFR

60-89 and kidney damage

25

CKD stage 3 GFR

30-59

26

CKD stage 4 GFR

15-29

27

CKD stage 5 GFR

28

Normal to mild increase in measured urine albumin

29

measured urine albumin termed a moderate increase

30-300

30

a severe increase in measured urine albumin

>300