Renal Diseases Flashcards

1
Q

what is glomerulonephritis?

A

injury to the glomeruli of the kidney
- results in glomerulus inflammation
- can be acute or chronic

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2
Q

what is glomerulonephritis often caused by?

A

immune complexes that build up as a result of bacterial infection of a system infection

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3
Q

what is pyelonephritis?

A

inflammation of the renal tubules
- results in

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4
Q

what is pyelonephritis often caused by?

A

untreated urinary tract infections

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5
Q

What is urea nitrogen?

A

a non-protein nitrogenous substance (NPN) found in serum

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6
Q

where and how is urea synthesised?

A

in the liver
it is converted from the excess ammonia left over from protein metabolism

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7
Q

what is Blood urea nitrogen (BUN)?

A

a retention test where the nitrogen portion of a urea sample that has been taken from the blood before the kidney has processed it

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8
Q

Chronic Kidney Disease (CKD)

A
  • gradual loss of kidney function over time
  • inefficient filtration of waste products and excess blood fluids
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9
Q

CKD Diagnosis

A
  • high levels of serum creatinine
  • decreased GFR
  • Identification of kidney damage for over three months (proteinuria - high protein in urine - or hematuria - blood in urea)
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10
Q

Acute Kidney Injury (AKI)

A
  • sudden loss of kidney function
  • often fixable
  • can result from causes such as dehydration, medications, severe infections
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11
Q

AKI diagnosis

A
  • High serum creatinine levels accumulated over a short period
  • Decreased urine output (less volume)
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12
Q

Glomerulonephritis

A

injury to the glomeruli of the kidney
- results in glomerulus inflammation
- can be acute or chronic
- can result from infections, dehydration, autoimmune diseases

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13
Q

Glomerulonephritis diagnosis

A
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14
Q

Polycystic Kidney Disease (PKD)

A
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15
Q

Nephrolithiasis (Kidney stones)

A
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16
Q

Nephrotic Syndrome

A
17
Q

Hematuria

A
18
Q

Glomerular Filtration Rate GFR

A
19
Q

Serum Creatinine

A
  • produced by muscle metabolism
  • waste product
  • secreted by the kidneys so high levels indicate reduced kidney functions
20
Q

Blood Urea Nitrogen (BUN)

A
  • measures nitrogen conc in blood
  • nitrogen comes from the breakdown of urea - produced in liver and secreted by the kidneys
  • high BUN levels = kidney dysfunction
  • less specific than GFR or serum creatine measurements
21
Q

Urine Albumin-to-Creatine Ratio (ACR)

A
22
Q

Urine Protein-to=Creatinine Ratio (PCR)

A
23
Q

Renal Imaging

A
24
Q

Kidney Biopsy

A
25
Q

Nuclear Medicine Scans

A