Renal Function Test Flashcards

1
Q

The standard tests used to measure the filtering capacity of the glomeruli

A

Clearance test

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2
Q

Stability of substance in urine during 24- hour urine collection

A

Clearance test

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3
Q

Clearance test Reported in

A

mL/min

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4
Q

STANDARD METHOD for GFR

A

Urea clearance test

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5
Q

Demonstrate progression of renal
disease or response to therapy

A

Urea clearance test

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6
Q

REFERENCE METHOD for GFR

A

Inulin clearance test

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7
Q

Not routinely done because of the necessity for
continuous IV infusion

A

Inulin clearance test

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8
Q

Inulin clearance test PRIMING DOSE:

A

25ml of 10% inulin solution

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9
Q

Inulin clearance test CONTINUOUS INFUSION:

A

500ml of 1.5% inulin solution

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10
Q

Inulin clearance test
REFERENCE VALUES: male

A

127 ml/min

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11
Q

Inulin clearance test
REFERENCE VALUES: female

A

118 ml/min

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12
Q

Most commonly used; screening method of GFR

A

Creatinine clearance

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13
Q

waste product of muscle metabolism

A

Creatinine clearance test

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14
Q

Creatinine clearance
REFERENCE VALUES: Male
◦ 75- 112 mL/ min  Female

A

85-125 mL/ min

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15
Q

Creatinine clearance
REFERENCE VALUES: Female

A

75- 112 mL/ min

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16
Q

Standard body surface

A

1.73 m2

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17
Q

Creatinine clearance MINUTES

A

1440 mins

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18
Q

Indirect estimate of GFR

A

Cystatin C

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19
Q

Completely reabsorbed by the PCT, hence its
presence in urine denotes damage to the
tubules

A

Cystatin C

20
Q

good procedure for screening and monitoring
GFR.

A

Cystatin C

21
Q

Cystatin C specimen

A

Serum or plasma (not fasting)

22
Q

Cystatin C increase level

A

Acute and chronic renal failure

23
Q

Cystatin C method

A

Immunoassay

24
Q

Dissociates from human leukocyte antigens
at constant rate and is rapidly removed
from the plasma by glomerular filtration.

A

Beta 2 microglobulin

25
A rise has been shown to be more sensitive indicator of decrease in GFR than creatinine clearance
Beta 2 microglobulin
26
Not reliable in patients who have history of immunologic disorders.
Beta 2 microglobulin
27
Beta 2 microglobulin method
Enzyme immunoassay
28
monitor patients already diagnosed with renal disease or at risk for renal disease.
Estimated glomerular filtration rate
29
the formulas are valuable when medications that require adequate renal clearance need to be prescribed
Estimated glomerular filtration rate
30
Stages of Chronic Kidney Disease : Kidney Damage with Normal or high GFR GFR:
> 90
31
Stages of Chronic Kidney Disease : Kidney Damage with Mild decrease GFR Gfr:
60- 89
32
Stages of Chronic Kidney Disease : Moderate decrease GFR Gfr:
30-59
33
Stages of Chronic Kidney Disease: Severe decrease GFR Gfr:
15-29
34
Stages of Chronic Kidney Disease : Kidney Failure Gfr:
<15 - dialysis
35
Ability of the tubules to reabsorb the essential salts and water that have been nonselectively filtered by glomerulus
Concentration test
36
specific gravity of urine before entering the renal tubules, will vary when the urine enters the renal tubules for the reabsorption process.
1.010
37
Patients were deprived of fluids for 24 hours prior to measuring specific gravity
Fishberg test
38
Compare the volume and specific gravity of urine of day and night urine samples
Mosenthal test
39
specific gravity is influenced by the number and density (molecular weight) of the particles.
Osmolality
40
FREEZING POINT OSMOMETERS Principle:
Freezing point depression
41
Temperature at which water and ice are in equilibrium and is related to solute concentration
Freezing point
42
Freezing point osmometer standard reference:
Sodium chloride
43
VAPOR PRESSURE OSMOMETERS Principle:
Measure dew point
44
VAPOR PRESSURE OSMOMETERS Standard reference
Sodium chloride
45
VAPOR PRESSURE OSMOMETERS Standard reference
Sodium chloride
46
test most commonly associated with tubular secretion and renal blood flow
P-aminohippuric acid test
47
The inability to produce an acid urine in the presence of metabolic acidosis
Renal tubular acidosis