Renal Physiology: Reabsorption and Secretion

Question 1

What is the electrical charge of the basement membrane of Bowmen’s Capsule?

Answer 1

Negative, which is why elements of positive charge can easily pass through

Question 2

What is net filtration pressure (NFP)

Answer 2

Forces favoring or opposing filtration

Question 3

What are the favoring forces of Bowmen’s Capsule pressure?

Answer 3

• Systemic arterial pressure
• Hydrostatic pressure in capillary

Question 4

What are the opposing forces of Bowmen’s Capsule pressure?

Answer 4

• Hydrostatic pressure in Bowman capsule space
• Oncotic pressure of glomerular capillary blood

Question 5

Where is bicarb resorbed to maintain acid-base balance?

Answer 5

Proximal convoluted tubule

Question 6

Intercalculated cells secrete ________ and absorb ______, to maintain acid-base regulation in the distal convoluted tubule

Answer 6

hydrogen, K+

Question 7

What are the main components of urine?

Answer 7

Water and urea

Question 8

Is urine usually basic or acidic?

Answer 8

Acidic

Question 9

What is the primary trace protein in urine?

Answer 9

Uromodulin

Question 10

Where is uromodulin made?

Answer 10

Loop of Henle

Question 11

What protein maintains intravascular volume?

Answer 11

Albumin

Question 12

What element is the key driver in extracellular space?

Answer 12

Na+

Question 13

What element is the key driver intracellularly?

Answer 13

K+

Question 14

What determines tonicity?

Answer 14

Extracellular Na+

Question 15

With elevated osmolarity this hormone will increase?

Answer 15

ADH

Question 16

During skeletal muscle contraction what is used for energy?

Answer 16

Creatine phosphate

Question 17

Creatinine is released with what type of metabolism?

Answer 17

Muscle metabolism

Question 18

Where is BUN reabsorbed?

Answer 18

Tubule

Question 19

When will BUN be increased?

Answer 19

Dehydration or acute/chronic renal disease, there is a decrease fluid through tubules and BUN will increase