Renal Tubular Acidosis

Question 1

Types of renal tubular acidosis:

Answer 1

• I distal: impaired H+ secretion
• II proximal: impaired HCO3- reabsorption
• IV impaired mineralocorticoid effecta: aldosterone deficiency

Question 2

Serum K in:
-Type I RTA:
-Type II RTA:
-Type IV RTA:

Answer 2

• Low
• Low
• High

Question 3

Which type(s) of renal tubular acidosis are associated with urine pH ≥ 5.5 (alkalotic)?

Answer 3

Type 1 RTA (distal)

Question 4

What is the recommended treatment for type I renal tubular acidosis?

Answer 4

Oral bicarbonate replacement

Question 5

Which renal tubular acidosis is highly associated with congenital anomalies (obstruction) of urinary tract?

Answer 5

Distal RTA (type 1)

Question 6

Which renal tubular acidosis may be caused by amphotericin B toxicity?

Answer 6

Distal RTA (type 1)

Question 7

What is the likely diagnosis in an elderly patient with diabetes with non-anion gap metabolic acidosis, hyperkalemia, and mild renal insufficiency?

Answer 7

Type 4 (hyperkalemic) renal tubular acidosis

Question 8

What is the recommended treatment for type IV renal tubular acidosis?

Answer 8

Fludrocortisone

Question 9

What is the recommended treatment for type II renal tubular acidosis?

Answer 9

Potassium citrate