Renal Tumors Flashcards Preview

Pathology 4 Quiz 2 > Renal Tumors > Flashcards

Flashcards in Renal Tumors Deck (26)
Loading flashcards...
0
Q

Regular growth pattern and cells free of atypia. Fronds.

A

Renal papillary adenoma

1
Q

What are the 4 most common benign tumors of the kidney?

A

Renal papillary adenoma, renal fibroma (hamartoma), angiomyolipoma, oncocytoma

2
Q

Uniform, large polygonal cells; Numerous prominent mitochondria

A

Oncocytoma

3
Q

What are the 5 primary malignant tumors of the kidney?

A

Renal cell carcinoma, papillary carcinoma, renal sarcomas, collecting duct tumors, Wilm’s tumor (nephroblastoma)

4
Q

Most common primary renal tumor of childhood

A

Wilm’s tumor (nephroblastoma)

5
Q

Which chromosome is affected in Wilm’s tumor?

A

11

7
Q

Large, well circumscribed lesion that is grayish-tan in color

A

Wilm’s tumor (nephroblastoma)

8
Q

nests of primitive appearing cells that stain deep blue or purple.

A

Wilm’s tumor

8
Q

What do Wilm’s tumor cells resemble?

A

the nephrogenic zone of the fetal kidney.

9
Q

Most common type of renal malignancy

A

Renal cell carcinoma

10
Q

Where do renal cell carcinomas originate?

A

within the renal cortex

11
Q

responsible for 80 to 85% of all primary renal neoplasms.

A

Renal cell carcinoma

12
Q

Classic triad of RCC

A

flank pain, hematuria and palpable abdominal mass.

13
Q

What is the major risk factor for RCCA?

A

tobacoo

14
Q

5-6% chronic dialysis pts develop

A

renal cell carcinoma

15
Q

tan to yellow in color in the gross specimen

A

Renal cell carcinoma

16
Q

What are 5 distinct cell types of renal cell carcinoma?

A

Clear cell carcinoma, chromophilic carcinoma, chromophobic carcinoma, oncocytic carcinoma, collecting duct carcinoma

17
Q

Most common cell type in RCC?

A

Clear cell

18
Q

From where do clear cell carcinomas arise?

A

Proximal tubule

19
Q

also arise from proximal tubule cells and are occasionally referred to as papillary renal carcinomas.

A

Chromophilic carcinomas

20
Q

originate from cortical collecting dust and are composed of sheets of cells which appear darker then cells of clear cell carcinoma.

A

chromophobic carcinomas

21
Q

arise from collecting duct cells and consists of large well differentiated neoplastic cells with a characteristic large number of mitochondria

A

Oncocytomas

22
Q

Classic histolgic features: neoplastic cells that have clear cytoplasm that are arranged in nests with intervening blood vessels.

A

Renal cell carcinoma

23
Q

Density is greater at the periphery of the tumor cells in which patients?

A

Chromophobic

24
Q

common sites for mets in RCCA?

A

lung, lymph nodes, bone, liver, brain, ipsilateral adrenal gland and contralateral kidney.

25
Q

Common cancers with mets to the kidneys

A

lung, breast, uterus, ovaries, stomach, intestines and pancreas.