repro

Question 1

antiestrogen on breast, proestrogen on endometrium and bone

Answer 1

tamoxifen

Question 2

blocks estrogen in hypothal (hyopthal thinks there isn’t enough estrogen)

Answer 2

clomiphene citrate (so inc LH and leads to ovulation)

Question 3

micronized natural progesterone

Answer 3

prometrim

Question 4

transvaginal natural progesterone

Answer 4

crinone

Question 5

synthetic progestins

Answer 5

medroxyprogesterone, norethinidrone, nogestrel megestrol

Question 6

progesterone only BC

Answer 6

norethindrone, nogestrel

Question 7

use of progestin BC only

Answer 7

estrogen contraindicated ie endometrial Ca history, lactating

Question 8

Estrogen/Progesterone BC combo physio

Answer 8

estrogen: suppress FSH thus preventing follicle maturation and LH surge.
Progesterone, suppress LH thus preventing ovulation, and thickens mucus so sprem can’t penetrate and atrophies endometrium.

Question 9

poscoital BC

Answer 9

levonorgestrel

Question 10

detachment of uterus

Answer 10

mifepristone (RU-486)

Question 11

ED meds

Answer 11

sildenafil citrate, vardenafil, tadalafil

Question 12

MOA ED meds

Answer 12

inhibit cGMP breakdown, dec Ca, smooth muscle relaxation, erection. CI with nitrates and alpha blockers