Flashcards in Repro - Female Deck (11):
1
hormones @ puberty
nighttime pulse GnRH
down sensitivity to negative feedback from gonadotrophs
2
hormones @ repro years
pulse GnRH
LH > FSH
E, P, inhibin, activin
3
hormones @ menopause
no more neg feedback from ovaries
LH, FSH go way up
FSH > LH (decrease in inhibin)
4
menstrual phases
follicular
ovulatory
luteal
5
follicular phase
day 0 - 14
goal: dev follicle, prep uterus for P
growth of dominant follicle --> E
E --> granulosa make more E
E --> up E and FSH receptors
E --> inhibit GnRH
FSH dip --> other follicles atresia
LH slowly increasing (need E and P to inhibit)
6
ovulatory phase
~12 hrs post LH surge
goal: release oocyte
when follicle mature, E:P up --> LH surge
LH surge --> stop E synth by follicle (inhibit aromatase)
LH --> reinitiate meiosis
LH --> prostaglandins --> ovulation
LH --> follicle change to luteal
7
luteal phase
14 days until menstruation
goal: form CL, up P, prep uterus
follicle dies --> E drops (- feed again)
inhibin - neg feed
LH stim CL to make E and P*
P inhibits LH and FSH
when CL dies --> LH drops
8
uterine phases (+ ovarian link)
menses (follicular)
proliferative (follicular)
secretory (luteal)
9
hormones to start menstruation
drop in E and P from dead CL
release of prostaglandins (contract vessels, contract myometrium)
10
proliferative phase
change endo from increased E
11