Repro - Female Flashcards Preview

Physiology > Repro - Female > Flashcards

Flashcards in Repro - Female Deck (11):
1

hormones @ puberty

nighttime pulse GnRH
down sensitivity to negative feedback from gonadotrophs

2

hormones @ repro years

pulse GnRH
LH > FSH
E, P, inhibin, activin

3

hormones @ menopause

no more neg feedback from ovaries
LH, FSH go way up
FSH > LH (decrease in inhibin)

4

menstrual phases

follicular
ovulatory
luteal

5

follicular phase

day 0 - 14
goal: dev follicle, prep uterus for P
growth of dominant follicle --> E
E --> granulosa make more E
E --> up E and FSH receptors
E --> inhibit GnRH
FSH dip --> other follicles atresia
LH slowly increasing (need E and P to inhibit)

6

ovulatory phase

~12 hrs post LH surge
goal: release oocyte
when follicle mature, E:P up --> LH surge
LH surge --> stop E synth by follicle (inhibit aromatase)
LH --> reinitiate meiosis
LH --> prostaglandins --> ovulation
LH --> follicle change to luteal

7

luteal phase

14 days until menstruation
goal: form CL, up P, prep uterus
follicle dies --> E drops (- feed again)
inhibin - neg feed
LH stim CL to make E and P*
P inhibits LH and FSH
when CL dies --> LH drops

8

uterine phases (+ ovarian link)

menses (follicular)
proliferative (follicular)
secretory (luteal)

9

hormones to start menstruation

drop in E and P from dead CL
release of prostaglandins (contract vessels, contract myometrium)

10

proliferative phase

change endo from increased E

11

secretory phase

due to increase in P
inhibit E
uterus secretes glycogen-rich secretion
endo CT becomes loose and edematous
inhibit contractions