Reproductive Flashcards

(76 cards)

1
Q

The ovaries secre what?

A

Estrogen

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2
Q

Is most testosterone free or bound?

A

98% bound, to plasma proteins (SSGB and albumin)

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3
Q

Can melatonin play a roll in onset of puberty ?

A

Yes

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4
Q

In what weeks do the testes begin to develop in males?

A

6-7

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5
Q

What is used to block the conversion from test to dihydrotestosterone ?

A

5a-recutase

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6
Q

Growth and development of the external genitalia happens at what week in utero and is dependent on what?

A

9-10 weeks, conversion of test to dihydrotesosterone

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7
Q

Lh stimulates what in the theca?

A

Cholesterol desmolase

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8
Q

Does the female genitalia require hormones ?

A

No

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9
Q

Growth of the tests is due primarily to what?

A

Increased number of seminiferous tubules which initiate spermatogeneisis

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10
Q

What promotes breast development ?

A

Estradiol

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11
Q

In what week do the ovaries develop in females?

A

Week 9

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12
Q

In the testes leydig cells synthesize what?

A

Testosterone

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13
Q

In boys when do they get pubic hair?

A

12-16

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14
Q

What stimulates secretory activity in the lobular ducts?

A

Both E and P

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15
Q

When does the growth spurt happen for girls?

A

11-14

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16
Q

In the ovaries theca cells synthesize what?

A

Progesterone

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17
Q

What is an ovarian steroid hormone?

A

17B hydroxysteroid dehydrogenase

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18
Q

In the testes germ cells produce what?

A

Spermatogonia

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19
Q

In the embryo antimullerian hormone causes what?

A

Atrophy of mullerian ducts

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20
Q

What three things make up sexual differentiation ?

A

Development of the gonads, internal genital tract, and external genitalia

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21
Q

Genetic sex is determined by what?

A

Sex chromosomes, XY in males, and XX in females

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22
Q

In what week are the gonads indifferent/bipotential?

A

5

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23
Q

A male genotype but a female phenotype is called what?

A

Androgen insensitivity syndrome

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24
Q

A Female who at puberty shows breasts development and no menstration as what?

A

Androgen insensitivity

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25
In the second and third trimesters
Estriol
26
In the embryo what testosterone does what?
Growth and differentiation of wolffian ducts
27
What do men lack in the testes?
21 B hydroxylase, 11B hydroxylase
28
Estrogen up regulates progesterone but....
Progesterone down regulates estrogen
29
Development of the mammary gland requires what hormone?
Estrogen
30
In the ovaries germ cells produce what ?
Oogonia
31
In a female when is FSH > LH?
Old age, gonatotropin secretion rates continue to rise
32
At what time of day are their large pulses of LH?
At night
33
What is the major androgenic hormone
Testosterone
34
What converts androstenedione to testosterone?
17B hydroxysteroid dehydrogenase
35
What are the only ovarian cells with FSH receptors?
Granulosa
36
Puberty is initiated by pulsatile secretion of what?
GnRh which drives FSH and LH
37
What stimulates milk production?
Prolactin
38
What is secreted first during the menstrual cycle progesterone or estrogen?
Estrogen
39
The follicular phase is dominated by what?
Estrogen
40
Growth of the structures of a female to normal size does require what hormone ?
Estrogen
41
When does ovulation happen during the menstrual cycle ?
Midpoint
42
The luteal phase is dominated by what?
Corpus luteum
43
When does menarche happen for girls?
10-16
44
In the ovaries Theca + granulosa cells synthesize what?
Estrogen
45
Is testosterone active in all androgenic target tissues?
No
46
When does the growth spurt happen for boys?
13-16
47
There are 3 ways maleness or femaleness can be characterized, what are they?
Genetic sex, gonadal sex, phenotypic sex
48
During the last half of pregnancy what is the hormone of highest concentration ?
Prolactin
49
The first 14 days of the menstrual cycle is called the what?
Follicular phase
50
What is used to tread benign prostatic hyperplasia and male pattern baldness?
Finasteride (propecia)
51
HPA in the testes is controlled by what kind of feedback?
Negative
52
What is the first sign of puberty in girls?
Budding of the breasts
53
Appearance of public hair (which precedes menarche) is dependent on what?
Increased secretions of adrenal androgens
54
What is an ovarian steroid hormone that converts testosterone to 17B estradiol ?
Aromatase
55
What stimulates formation of the corpus luteum and maintain progesterone production during the luteal phase?
LH
56
What kind of testosterone is biologically active?
Free
57
When does breast development take place
11-15
58
If you remove the pineal gland what effect will that have on puberty?
It will cause earlier onset
59
In some tissue testosterone is converted to dihydrotestosterone by what?
5a- reductase
60
In the testes sertoli cells synthesize what?
Antimullerian hormone, inhibin
61
Gonadal sex is determined by what?
By what gonads are present
62
The last 14 days of the menstrual cycle is called what?
Luteal phase
63
In a female when is LH> than FSH ??
During adult reproductive age
64
What is the ration of progesterone to estrogen ?
150-1
65
What to hormones are required for the male phenotype and are secreted by the testes?
Antimullerian hormone and testosterone
66
What hormone is used to induce labor?
Oxytocin
67
When does penile growth take place?
13-15
68
Genetic sex usually determines_________sex?
Gonadal
69
In girls when do they get pubic hair ?
9-15
70
What induces milk let down?
Oxytocin
71
FSH stimulates what in the granulsoa cells?
Aromatase
72
In the first trimester what hormone is high?
HCG
73
The testes have what additional enzyme ?
17 B-hydroxysteroid dehydrogenase
74
Ovulation is initiated by what?
LH
75
Both functions of the testes are controlled by what?
HPA
76
Phenotypic sex is determined by the physical characteristics of what?
Internal genital tract and external genitalia