Reproductive Physiology Flashcards

(46 cards)

1
Q

Why is sexual reproduction favored over simple cloning in most animals?

A

It introduces genetic variability through recombination, helping species adapt and avoid perpetuating “bad” traits

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2
Q

What is parthenogenesis?

A

A form of asexual reproduction in which females produce offspring (clones) without fertilization (e.g., aphids in spring/summer).

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3
Q

How do some aphids switch to sexual reproduction in autumn?

A

Environmental cues (shorter days, cooler temps) trigger them to make males and eggs, ensuring genetic diversity and overwintering.

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4
Q

What are the two main purposes of meiosis?

A
  1. Reduce chromosome number from 2n → n
  2. Shuffle genes (crossing‑over) to create diverse gametes
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5
Q

During which meiotic phase does crossing‑over occur?

A

Prophase I—homologous chromosomes pair and exchange segments, generating new allele combinations.

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6
Q

How many gametes result from one meiotic cycle?

A

Four genetically distinct haploid (n) cells.

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7
Q

Define gonads.

A

Organs that produce gametes—testes in males, ovaries in females.

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8
Q

In the testis “balloon” model, what do the “spaghetti” represent?

A

The seminiferous tubules, where sperm develop; held in the “balloon” (tunica), bathed in interstitial fluid.

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9
Q

What cell types fill the interstitial space between seminiferous tubules?

A

Leydig cells (produce testosterone), blood vessels, nerves, and connective tissue.

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10
Q

Name the two key requirements for successful gamete production & fertilization.

A
  1. Viable gametes (made & stored)
  2. Delivery system for sperm → egg (e.g. ducts, copulation)
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11
Q

What triggers seasonal breeding in some mammals (e.g., deer)?

A

Photoperiod (day length) and hormonal signals that switch gonadal activity on/off.

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12
Q

Give one example of regeneration in animals and its research significance.

A

Planarian flatworms regrow entire bodies after fragmentation—model for understanding tissue regeneration.

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13
Q

Why study diverse species (insects, slugs, plants) in reproductive physiology?

A

Each offers unique mechanisms (e.g. parthenogenesis, regeneration, seasonal breeding) that inform broader biological principles.

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14
Q

What is the end goal of all reproductive strategies?

A

Successful offspring production and survival to carry on the species.

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15
Q

Why can’t somatic (body) cells undergo meiosis?

A

Only germ cells in the gonads have the specialized machinery to perform reduction division and generate gametes.

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16
Q

What is the function of the blood-testis barrier?

A

Prevents immune system attack on developing sperm by isolating them from blood.

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17
Q

What are the two main cell types in seminiferous tubules?

A

Sertoli cells (support, nourish, regulate sperm development)
👉 Spermatogenic cells (develop into sperm)

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18
Q

What is the role of Sertoli cells?

A

Support spermatogenesis, form the blood-testis barrier, and facilitate meiosis and sperm release.

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19
Q

What process forms sperm from stem cells?

A

Spermatogenesis, which includes mitosis, meiosis I & II, and differentiation.

20
Q

Where does spermatogenesis occur?

A

inside seminiferous tubules in the testes.

21
Q

What are the three parts of a sperm?

A

Head (DNA + acrosome), Neck (mitochondria), Tail (flagellum for motility)

22
Q

Why are many sperm needed for fertilisation?

A

To break barriers around the egg and ensure one successful fertilisation.

23
Q

What is sperm maturation and where does it occur?

A

Maturation = sperm becomes motile and fertilising
👉 Happens in the epididymis

24
Q

What is the function of the epididymis?

A

Stores and matures sperm; adds surface proteins (antigens).

25
Why are testes outside the body in a scrotum?
Spermatogenesis requires temperature 2–4°C lower than body temperature.
26
. What do Leydig cells do?
Produce testosterone and INSL3 (insulin-like hormone 3)
27
What stimulates Leydig cells?
Luteinising hormone (LH) from the pituitary gland.
28
What does INSL3 do?
Drives testicular descent during fetal development.
29
. What is cryptorchidism?
Failure of testes to descend; causes infertility if untreated.
30
How many sperm per millilitre in a normal ejaculate?
20–120 million/ml 👉 <10 million = oligospermia (low fertility)
31
What is the average length of the menstrual cycle?
Around 28 days (varies from 26–32 days); consistent within individuals.
32
When are a female’s egg follicles established?
During fetal development — late 1st to early 2nd trimester.
33
: What is follicle atresia?
Natural degeneration and death of follicles at all stages of development.
34
What is recruited in each cycle from the ovarian reserve?
100–200 follicles; only one typically ovulates.
35
What is menopause caused by?
Depletion or poor quality of remaining follicles (loss of ovarian reserve).
36
What is the role of granulosa and theca cells in a growing follicle?
Granulosa (inner, hormone-secreting), Theca (outer, vascularised, hormone-producing).
37
: What is follicular fluid?
Hormone-rich fluid secreted by granulosa cells forming the antrum in mature follicles.
38
What is the name of the fully mature follicle?
Graafian follicle.
39
What triggers ovulation?
LH surge, which follows peak oestrogen levels.
40
: What is formed after ovulation from the remaining follicle cells?
Corpus luteum — secretes progesterone to support potential pregnancy.
41
What happens if there is no fertilisation?
Corpus luteum regresses; endometrium sheds = menstruation.
42
What ensures the egg is picked up after ovulation?
Cilia in the fimbriae of the fallopian tube beat to guide the egg.
43
What is endometriosis?
Uterine tissue grows outside the uterus, often due to misdirected ciliary action.
44
What are the two main phases of the menstrual cycle?
Follicular phase (oestrogen-dominated) & luteal phase (progesterone-dominated).
45
What hormone maintains the uterine lining post-ovulation?
Progesterone from the corpus luteum.
46
When is the best chance of conception?
Within 2 days before or after ovulation (fertile window).