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Flashcards in research ebm Deck (28):
1

COMPONENTS OF THE EBM CYCLE

A. Asking the Question
B. Searching the Literature
C. Appraising the Evidence
D. Integrating the Data
E. Making a Decision

2

PICOM components

 Population to be studied 
Intervention or exposure = Independent variable
Comparisons to be made (control) 
Outcome of interest = Dependent variable  Methodologic (study design)

3

Research question

PICOM
PIO

4

“To evaluate, to judge the value/worth”

APPRAISING THE EVIDENCE

5

COMPONENTS OF CRITICAL APPRAISAL

VALIDITY / LACK OF BIAS
SIZE & PRECISION OF EFFECT
APPLICABILITY & IMPACT

6

Will the results help me in caring for my patients?

APPLICABILITY & IMPACT

7

What are the results?

SIZE & PRECISION OF EFFECT

8

 Is the study valid?

VALIDITY / LACK OF BIAS

9

W/ SYSTEMATIC ERROR
= BIASED

NOT VALID

10

Accuracy

Validity

11

Reliability

Precision

12

INTEGRATIVE STUDY DESIGNS

REVIEWS
OVERVIEWS
META-ANALYSIS
GUIDELINE DEVELOPMENT

13

results of trials are combined statistically

META-ANALYSIS

14

The PRIME requirement of any study

Validity

15

= W/ RANDOM ERROR
= LOW SAMPLE SIZE

Precision

16

any 2 articles (or more)

REVIEW

17

Lack of significant bias

Validity

18

PHRASE THE QUESTION PRECISELY, IDENTIFYING CONCEPTS P, I, O and M.

STEP 1 IN CONDUCTING AN EFFICIENT LITERATURE SEARCH

19

actual recommendations on management are made

GUIDELINES

20

“Repeatability”

Precision

21

EXPAND AND INTERSECT THE CONCEPTS SEQUENTIALLY AS NEEDED

STEP 3 IN CONDUCTING AN EFFICIENT LITERATURE SEARCH

22

comprehensive, systematic and objective search of the literature based on a research question

OVERVIEW

23

CHOOSE THE SEARCH METHOD.

STEP 2 IN CONDUCTING AN EFFICIENT LITERATURE SEARCH

24

Consistency

Precision

25

EXAMINE YIELD FOR MISHITS AND MISSES AND MODIFY SEARCH IF NECESSARY.

STEP 4 IN CONDUCTING AN EFFICIENT LITERATURE SEARCH

26

Two search methods

FREE TEXT SEARCHES
MeSH

27

Which is which: free text or MeSH

SHORTER; MORE SYSTEMATIC
NEW TERMS AVAILABLE

SHORTER; MORE SYSTEMATIC :MeSH adv
NEW TERMS AVAILABLE : free text adv

28

Which is which: free text or MeSH

LONG STRATEGY; SUBJECT TO USER ERROR
NEW TERMS UNLISTED; SUBJECT TO CLERICAL ERROR

LONG STRATEGY; SUBJECT TO USER ERROR
Free text: disadvantaged

NEW TERMS UNLISTED; SUBJECT TO CLERICAL ERROR
MeSH: disadvantaged