Research Exam Flashcards
(28 cards)
What is the Hierarchy of Evidence?
- N of 1 RCT
- Multiple patient randomized trials
- Observational studies
- Basic research
- Clinical experience
What are the 3 ways to use medical literature?
- Staying alert to important new evidence
- Problem solving
- Asking background (novice) and foreground (expert) questions
What does PICO stand for?
Patient
Interventions
Comparison
Outcome
What does PECO stand for?
Population
Exposure
Comparison
Outcome
What is apprasial?
How serious is the risk of bias and what are the results
What are the four domains of practice?
Diagnosis
Prognosis
Intervention
Harm
What is evidence-based practice?
integration of best research evidence, clinical expertise and pt values
What are the 6 steps of EBM Method?
- Acknowledge something I know
- Formulate PICO
- Search databases
- Select best available evidence
- Integrate evidence with clinical practice and pt values
- Periodically evaluate self
What are the 3 fundamentals of EBM?
Optimal clinical decision making
Guidance
Evidence alone is never sufficient
What does SORT stand for?
Strength-of- Recommendation Taxonomy
SORT = A
consistent, good quality pt oriented evidence
SORT= B
Inconsistent or limited quality pt oriented evidence
SORT= C
consensus, disease oriented evidence, usual practice, expert opinion, or case series for studies of dx, tx, prevention or screening.
How many levels of evidence is there?
1-5
What are the 5 types of foreground questions?
Therapy Harm Ddx Dx Prognosis
What study is more common?
observational cohort study
What stats are seen in cohort studies?
incidence
What stats are seen in cross-sectional studies?
prevalence
What study design is good for rare diseases?
case-control
What is sensitivity
probability a person WITH a dz will test +
What is specificity?
probability a person WITHOUT a dz will test -
A NEG result from a highly senstive test will what?
RULE OUT the disease
A POS result from a highly specific test will what?
RULE IN the disease
PLR should be over ? is significant?
5
