Research Studies Flashcards

(43 cards)

1
Q

IRB Exemption

A

-chair gives exemptions
-pose little risk
-does not involve a sensitive topic or population
-educational

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2
Q

IRB Expedited

A

-subset of board reviews it
-minimal risk (surveys, healthhy pops, non invasive, existing data)
-no interventions

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3
Q

IRB Full

A

-entire board reviews
-more than minimal risk
-sensitive topic or populations
-any research with an intervention

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4
Q

IRB Application Contents

A

-additional questions about study plans
-informed consent
-apropriate management of data

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5
Q

Informed Consent

A

-informed
-can opt out
-lay language (6th grade)
-answet questions
-contact info
-sign
-voluntary

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6
Q

Evidence Based Practice

A

integration of:
-evidence
-clinical expertise
-patient values

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7
Q

PubMed

A

-access to medline
-best source for RCT

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8
Q

Medline

A

-National library of medicine’s database

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9
Q

Primary Sources

A

-only clinical trials
-RCT, cohort, case control

-current but must read it all

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10
Q

Cochrane

A

-database for systematic reviews

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11
Q

Hierarchies of Evidence

A

-1a-5
-A-F

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12
Q

Systematic Reviews of RCT

A

-1a
-review or meta analysis of RCT

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13
Q

Randomized Control Trials

A

-1b
-group randomized into experiemental groups
-narrow confidence interval

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14
Q

All or None

A

-1c
-all Pt died before but some lived after
-some pt died before but none died after

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15
Q

Systematic Review of Cohort Studies

A

-2a
-review or meta analysis of cohort studies

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16
Q

Cohort Studies

A

-2b
-already in a group and compare different treatments

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17
Q

Outcomes Research

A

-2c
-how much value does it give to the pt
-not experimental

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18
Q

Systematic Review of Case Control

A

-3a
-review or meta analysis of Case control studies

19
Q

Case Control Studies

A

-3b
-find people with outcome and control that dont have outcome
-look back in time to find possible causes

20
Q

Case Study or Series

A

-4
-detailed analysis of cases

21
Q

Bench Research

A

-5
-non human research

22
Q

Expert Opinion

23
Q

Grades

A

A-F
A: strong evidence, level 1 study
F: expert opinion

24
Q

PEDro

A

-tool to measure the quality of RCT
-0-10, 6 being good

25
Quadras
-measure the quality of a study that investigattes accuracy of a test) outcome meausure 0-14, 7 being good
26
Introduction
-purpose statement -what is the problem -why is it important -what is the purpose
27
Hypopthesis
Null: no different between x and y Alternative: there will be a difference between x an y -can reject or fail to reject your null
28
Methods
-Participants: why and who, when, how -Instrumentation: validity, outcome measures, interventions -Procedures: must be reproducible -Data Analysis: explain how the data was handled
29
Results
-Outcomes of analysis -tables and graphs -no interpretation of data
30
Discussion
-compared to previous literature -implications -strengths of the study -limitations -interpretations
31
Conclusion
-overview of study -overview of findings
32
Meta Analysis
-systemic review with calculations of each study -forest plot
33
Order of Parts of a Study
Abstract Intro Methods: participants Methods: instrumentation Methods: procedures Methods: data analysis Results Discussion Conclusion
34
Descriptive Studies
-Retrospective -Normative -qualitative -describes data
35
Exploratory Studies
-correlational: relationships -predictive: reliability and validity -case control and cohort (quasi experimental)
36
Experimental Studies
-RCT only true -cause and effect
37
One-Way Repeated Research Design
-one group doing the same thing over titme
38
Posttest-Only Randomized Group
-randomized -2 or more groups that are only measured after the intervention
39
Posttest-Only Non-Randomized Research Design
-non randomized -2 or more groups that are only measured after the intervention
40
Factorial-Fully Independent Research Design
-2+ interventions at the same time -each person stays in the same group the whole time
41
Factorial-Fully Repeated Research Design
-2+ interventions at the same time -all participants switch groups throughout the study
42
Factorial Mixed/Split Plot Research Design
-with or without randomization -Multiple interventions (independent groups) move through time -one intervention vs another; pre post post 2 -most common in PT
43
Crossover Research Design
-with or without randomization -groups switch interventions after 1st is done