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Flashcards in Research Synopses Deck (8)
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He is investigating the renoprotective effects of electrophilic nitro-fatty acids, which modulate inflammatory activation and induce cytoprotective antioxidant responses.



He studies brain-computer interface (BCI) implementations in sensory regions of the brain. He's currently implementing a BCI using intracortical neural recordings in the visual cortex to provide auditory feedback on neural activity. His goals are to assess how well non-human primates can control neurons in visual cortex and to better understand the relationship between neural activity and visual attention.



His research incorporates expert prior knowledge into machine learning algorithms and applies them to learn novel clinical knowledge from limited datasets. He focuses on how expert knowledge can improve missing value imputation, discretization, and Bayesian network-based rule learning algorithms.



He studies how evolution in genome structure (such as gene fusions and copy number variations) mediates metastasis and therapy resistance in advanced women's cancers. He is generating and integrating multiplatform sequencing data on two cohorts of patient-matched tumor pairs -- primary breast cancers / brain metastases and ovarian cancer primaries / recurrences.



He studies how stem cell incorporation into nerve conduits can provide a dynamically changing environment for neurotrophic factors and immunomodulatory cytokine release, which can allow for nerve regeneration superior to autografting. He is incorporating stem cells into nerve conduits during the conduit fabrication process and applying them in in vitro and in vivo models of peripheral nerve injury.



He uses various behavioral and neuroimaging techniques to elucidate the mechanisms that underlie perceptual behavior after brain injury or surgery and in developmental disorders. Right now, he is exploring EEG signatures of congenital prosopagnosia (developmental face blindness).



He studies heme biochemistry, with a specific focus on the recently discovered proteins cytoglobin and neuroglobin. He characterizes the wild-type proteins and generates recombinant mutants that may show promise for specific clinical applications.



She studies the relationship between Th17 cells, the microbiome, and autoimmunity. Specifically, She is utilizing the mouse model of Multiple Sclerosis, experimental autoimmune encephalomyelitis (EAE), to investigate how dysregulation of enteric Th17 signaling and the commensal microbiota influence the pathogenesis of autoimmune diseases such as MS.