Resistance to antimicrobal agents Flashcards
(16 cards)
Name the B Lactam antibiotics…
Penicillin
Cephalosporins
Monobactams
Carbapenems
What do B Lactam antibiotics do?
Bind to penicillin binding proteins to break down cross links
Do not take antibiotics for…
Viral infections
Do not save…
Antibiotics for next time your sick
Complete the course even if…
You’re feeling better
Antibiotic associated colitis is caused by the bacterium…
C.Diff
C.Diff is a…
Gram + rod
The C.Diff bacteria can produce…
Spores
C.Diff may cause… (3)
Diarrhoea
Pseudomembranous colitis
Toxic megacolon
Why may antibiotics cause C.Diff to become prevelant?
They can upset the normal gut flora and this provides colonisation resistance which can lead to infection
Resistant genes are carried on…
Plasmids
Spread of antibiotic resistance is termed…
Conjugation
Name some abx that attack the cell wall…
Vancomycin Penicillins Moncobactems Carbapenems Cephalosporins Bacitracin Cycloserine
Name some abx that attack protein synthesis…
Erythromycin (quite a few that end in MYCIN) BUT NOT VANCOMYCIN!!!!!!!!!!!!!!!
Chloramphenicol
Name some abx that attack DNA synthesis…
To be continued
Why do abx not kill our cells?
They selectively kill bacteria or act on processes unique to bacteria
