Resp Flashcards

1
Q

what sign do you get in bronchiectasis on CT?

A

signet ring due to bronchioles being bigger than adjacent

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2
Q

common sites of mets for lung cancer?

A

brain, liver, bone

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3
Q

small cell lung cancer associated with which syndrome?

A

lambert eaton

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4
Q

which caner expresses TTF1 ?

A

adenocarcinoma

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5
Q

mucous producing tumours seen in peripheries of lungs?

A

adenocarcinoma

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6
Q

keratinized tumour that found centrally and frequently cavitates

A

squamous cell

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7
Q

what does squamous cell secrete ?

A

PTH

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8
Q

if lung cancer invades sympathetic chain, which syndrome can you get?

A

horners syndrome

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9
Q

pleural tap - where is fluid taken from ?

A

pleural cavity

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10
Q

in general, small cell cancers are more? (chemo/radio sensitive)

A

chemosensitive

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11
Q

which cancer develops as a result of asbestos exposure

A

malignant mesothelioma

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12
Q

what do you see on x ray in mesothelioma?

A

recurrent pleural effusions

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13
Q

what is pleurodesis?

A

adhere the two lung surfaces together

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14
Q

bibasal, fine end inspiratory crackles

A

IPF

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15
Q

management of IPF?

A

not much can be done
50% will be dead in 5 years
anti fibrotic agent = perfenidone

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16
Q

calcium in sarcoidsis ?

A

high

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17
Q

in sarcoisosis, you get increase in serum?

A

ACE

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18
Q

honey comb lung

A

extrinsic allergic alveolitis

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19
Q

extrinsic allergic alveolitis - what kind of hyersensitivtiy?

A

type 3

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20
Q

egg shell calcification at hilar nodes?

A

silicosis

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21
Q

asbestosis can lead to ?

A

asbestosis

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22
Q

influenza cuased by influenza?

A

A and B

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23
Q

pseudo membrane formation?

A

diptheria

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24
Q

rusty red sputum?

A

strep pneumonia

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25
comes in waves every 4 years?
mycoplasma pneumonia
26
mycoplasma pneumonia most likely to infect?
children and elderly
27
coxiella spread from?
animals such as sheep and goats
28
all atypical pneumonias respond to clarithromycin
y
29
bilateral cavitating pneumonia?
staph aureus
30
pneumonia that alcoholics/elferly/diabetics/neuro musclar disease get ? presents with red jelly like sputum
klebsiella (kronenburg)
31
pneumocystis pneumonia - who gets this?
immunocmpromised _ HIV
32
pneumocstis - treated with?
co trimaxazol
33
pneumonia seen in patients with CF/bronchiectasis?
pseudamonas ( treated with ciprofloxacin)
34
how would legionella present?
colonises water tanks - seen in those who have been abroad. presents with dry cough, flu like symptoms and GI upset
35
biochem in legionella?
hyponatraemia
36
what is CURB 65
measure of severity of community acquired pneumonia ``` confusion Urea over 7 resp rate over 30 bp <90 <65 age over 65 ```
37
1st line tx of community acquired pneumonia if nil by mouth ?
IV clarithromycin
38
severe community acquired pneumonia severe
co amox and dox
39
severe CAP and pen allergic
levofloxacin + dox
40
in ITU with CAP?
co amoxiclav and clarithromycin
41
in ITU with pen allergy?
levofloxacin and clarithromycin
42
non severe hospital acquired?
oral amoxicilin and metronidazole
43
severe hospital acquired step down ?
co trimoxazole and metronidazole
44
TB affects which part of the lungs?
upper
45
lesion at primary site of infection in lungs is called?
gohn focus
46
granulomas heal with?
calcification
47
dermatological of TB?
erythema nodosum
48
TB on chest x ray?
o Consolidation. o Cavitating upper lobe lesions. o Bilateral hilar lymphadenopathy. Latent: fibrosis, calcified lesions
49
what is the test called on sputum sample
zeil neilson. can also do PCR
50
what is the tuberculin skin test called?
mantoux test
51
which drug turns body fluids orange ?
rifampicin
52
categories of pleural effusion - more than 30g/l
exudate - malignancy, infection PE
53
what is the triad of MEIGS syndrome?
ascites, pleural effusion, benign ovarian tumour
54
D sign on x ray?
empyema
55
turbid yellow empyema ?
empyema
56
lymphocytes
malignancy TB autoimmune
57
most common mutation in CF?
deltaF508
58
investigations for CF?
genetic screening | sweat test - chloride > 60 mmol
59
hypoxia is defined as oxygen less than?
8
60
signs of hypercapnia?
morning headache, peripheral vasodilation, tachycardia, bounding pulse,
61
type 1 respiratory failure ?
low oxygen | low or normal co2
62
target sats in type 1 resp failure?
94-98%
63
type 2 resp failure ?
low oxygen high co2 target sats 88-92
64
what is cor pulmonale?
right sided heart failure
65
when can you send a pneumothorax home?
less than 2 cm and no SOB
66
do you have to inform DVLA of sleep apnea?
yes
67
pulmonary oedeam management ?
``` LMNOP loop diuretic morphine nitrate oxygen posture - sit up ```
68
why is morphine used in pulmonary oedema?
it has vasodilator properties