Respiration Flashcards
(19 cards)
Respiration equation
C6H12O6 + 6O2 -> 6CO2 + 6H2O + Energy
Respiration definition
The metabolic process where a large amount of ornery is released form the splitting of glucose into CO2 and H2
Stages of respiration
Glycolysis -> Link reaction -> Krebs cycle -> Oxidative phosphorylation
Basal metabolic rate
Minimum energy requirement of the body at rest to fuel basic metabolic processes
Phosphorylation
ADP + Pi -> ATP
Hydrolysis
ATP broken down into P and ADP
How does hydrolysis of ATP provide energy for cells
Energy is released from the bonds forming between H2O and P as the phosphate group is hydrolysed
Products of glycolysis
2 x ATP, 2 x Reduced NAD and 2 x pyruvate
Location of glycolysis
Cytoplasm
Glycolysis stages
- 2 ATP molecules add 2 Pi groups to glucose, causing it to split into 2 triose phosphate molecules (3C)
- 2 NAD molecules oxidise these 3 carbon molecules, forming 2 reduced NAD, and converting it into pyruvate
- 4 phosphate are transferred to 4 ADP molecules, phosphorylating into ATP
Link reaction stages
- Pyruvate is decarboxylated, CO2 is removed
- 2 Hydrogen are used to reduce NAD
- Pyruvate converted to acetate
- Coenzyme A combines with acetate to from Acetyl Coenzyme A
Products of link reaction
For half a glucose there is ONE Acetyl Coenzyme A, reduced NAD and CO2
Krebs cycle stages
- Acetyl Coenzyme A combines with 4C molecule to produce 6C molecule
- 6C molecule is decarboxylated and oxidised to release CO2 and reduced NAD to form 5C molecule
- 5C molecule is decarboxylated to release more CO2
- ATP is formed through substrate level phosphorylation
- 5C molecule is oxidised to release 2 reduced NAD and 1 reduced FAD
- This produces a 4C molecule to be used again
Products of Krebs cycle
4C molecule Coenzyme A 2 x CO2 3 x redcued NAD 1 x FAD 1 x ATP
Oxidative phosphorylation
Where energy from electrons on reduced NAD/FAD are used to make ATP
This involves the electron transport chain and chemiosmosis
Electron Transport Chain stages
- Reduced Coenzymes NAD/FAD release hydrogen atoms which split into H+ and e-
- The electrons move along electron transport chain via redox reactions (inner mitochondrial membrane)
- Energy from this process is used to pump H+ across the inner mitochondrial membrane creating a high H+ concentration in the intermembranal space
- ATP synthase helps moves H+ back down electrochemical gradient into matrix and synthesises phosphorylation of ATP (chemiosmosis)
- H+ and e- combine with O2 from the blood to form water, as oxygen is the final electron acceptor
How many ATP created from reduced NAD
3 ATP
How many ATP produced from reduced FAD
2 ATP
Total number of ATP produced per glucose molecule
38
8 from Glycolysis (2 ATP and 2 reduced NAD)
6 from Link Reaction occurring twice (2 reduced NAD)
24 from Krebs Cycle occurring (2 ATP, 6 reduced NAD and 2 reduced FAD)