Respiratory Flashcards

(36 cards)

1
Q

COPD management?

A

SABA or SAMA (ipratropium) first line as PRN

If remains breathless, determine if has asthmatic/steroid responsive symptoms:

  • Previous diagnosis of asthma or atopy
  • High eosinophils
  • Variation in FEV1 over time (at least 400ml)
  • Diurnal peak expiratory flow variation.

No asthma features
- Add LAMA and LABA regularly

Asthma features:
- Add LABA and ICS

For both, if no improvement: LAMA, LABA and ICS regularly along with SABA PRN

Moculytics - if chronic cough
Theophylline if the above doesn’t work/can’t tolerate
Prophylactic abx - azithromycin in some pts

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2
Q

Deep sea diving rules for those whom have had pneumothoraxes?

A

Avoid life long unless had pleurectomy

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3
Q

Peripheral tingling during exercise makes what diagnosis more likely?

A

Dysfunctional breathing

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4
Q

Restrictive picture on spirometry?

A

Ratio >70% and FVC decreased, FEV1 normal/reduced

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5
Q

Bronchiectasis and eosinophilia in a question likely allude to what?

A

Allergic bronchopulmonary aspergillosis - allergic reaction to aspergillus

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6
Q

CURB-65 score factors?

A

C Confusion (abbreviated mental test score <= 8/10)
U urea > 7 mmol/L
R Respiration rate >= 30/min
B Blood pressure: systolic <= 90 mmHg and/or diastolic <= 60 mmHg
65 Aged >= 65 years

(in primary care take away U)

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7
Q

CURB score thresholds?

A

consider home-based care for patients with a CURB65 score of 0 or 1 - low risk (less than 3% mortality risk)

consider hospital-based care for patients with a CURB65 score of 2 or more - intermediate risk (3-15% mortality risk)

consider intensive care assessment for patients with a CURB65 score of 3 or more - high risk (more than 15% mortality risk)

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8
Q

Asthma treatment guidelines?

A
  1. Newly-diagnosed asthma
    - Short-acting beta agonist (SABA)
  2. Not controlled on previous step OR Newly-diagnosed asthma with symptoms >= 3 / week or night-time waking
    - SABA + low-dose inhaled corticosteroid (ICS)
  3. If not controlled:
    - SABA + low-dose ICS + leukotriene receptor antagonist
    (LTRA)
  4. Next:
    - SABA + low-dose ICS + long-acting beta agonist (LABA)
    - Continue LTRA depending on patient’s response to LTRA
  5. Next:
    - SABA +/- LTRA
    - Switch ICS/LABA for a maintenance and reliever therapy (MART), that includes a low-dose ICS
  6. Next:
    - SABA +/- LTRA + medium-dose ICS MART
    OR consider changing back to a fixed-dose of a moderate-dose ICS and a separate LABA
  7. Next:
    - SABA +/- LTRA + one of the following options:
    – increase ICS to high-dose (only as part of a fixed-dose regime, not as a MART)
    – a trial of an additional drug (for example, a long-acting muscarinic receptor antagonist or theophylline)
    seeking advice from a healthcare professional with expertise in asthma
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9
Q

Urgent CXR for cancer in primary care for which patients?

A

Offer an urgent chest x-ray (to be performed within 2 weeks) to assess for lung cancer in people aged 40 and over if they have 2 or more of the following unexplained symptoms, or if they have ever smoked and have 1 or more of the following unexplained symptoms:

  • cough
  • fatigue
  • shortness of breath
  • chest pain
  • weight loss
  • appetite loss

Consider an urgent chest x-ray (to be performed within 2 weeks) to assess for lung cancer in people aged 40 and over with any of the following:

  • persistent or recurrent chest infection
  • finger clubbing
  • supraclavicular lymphadenopathy or persistent cervical lymphadenopathy
  • chest signs consistent with lung cancer
  • thrombocytosis
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10
Q

In pleural aspiration what does the pH level determine?

A

If below 7.2 then chest drain should be placed if they are ?infection

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11
Q

Criteria for discharge in an asthmatic exacerbation?

A
  • The patient being stable on their discharge medication (i.e no nebulisers or oxygen) for 12-24 hours
  • The inhaler technique being checked and recorded
  • PEF >75% of the best or predicted.
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12
Q

Criteria for moderate asthma attack?

A

PEFR 50-75% best or predicted
Speech normal
RR < 25 / min
Pulse < 110 bpm

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13
Q

Criteria for severe asthma attack?

A

PEFR 33 - 50% best or predicted
Can’t complete sentences
RR > 25/min
Pulse > 110 bpm

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14
Q

Criteria for life-threatening asthma attack?

A
PEFR < 33% best or predicted
Oxygen sats < 92%
'Normal' pC02 (4.6-6.0 kPa)
Silent chest, cyanosis or feeble respiratory effort
Bradycardia, dysrhythmia or hypotension
Exhaustion, confusion or coma
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15
Q

Causes of an obstructive picture on siprometry?

A

COPD
Asthma
Bronchiectasis

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16
Q

Common causes of bilateral hilar lymphadenopathy?

A

Sarcoidosis and TB

17
Q

Do you follow-up/monitor pleural plaques?

A

Nah.

Benign. They are not associated with cancer.

18
Q

When would you start BiPAP for COPD exacerbation?

19
Q

If COPD exacerbation still getting worse despite NIV what is next course of action?

20
Q

Contraindications to bupropion?

A

epilepsy, pregnancy and breast feeding.

Having an eating disorder is a relative contraindication

21
Q

Smoking cessation drugs to offer? Can you combine?

A

NRT, varenicline or bupropion

Not in any combination

22
Q

When talking acid-base status, if there has been some effort to compensate but it is still abnormal that is called?

A

partially compensated

23
Q

Exudate and transudate protein level, what is lights criteria?

A

exudates have a protein level of >30 g/L, transudates have a protein level of <30 g/L

if the protein level is between 25-35 g/L, Light’s criteria should be applied. An exudate is likely if at least one of the following criteria are met:

  • pleural fluid protein divided by serum protein >0.5
  • pleural fluid LDH divided by serum LDH >0.6
  • pleural fluid LDH more than two-thirds the upper limits of normal serum LDH
24
Q

Most common SEs of varenicline?

25
For COPD retainers if critically ill what O2 therapy should be given?
In patients who are critically ill (anaphylaxis, shock etc) oxygen should initially be given via a reservoir mask at 15 l/min. Hypoxia kills
26
Acute presentation of mitral stenosis?
Dyspnoea Atrial fibrillation Malar flush on cheeks Mid-diastolic murmur
27
Classic presentation of granulomatosis with polyangiitis?
pulmonary haemorrhage (haemoptysis), renal impairment (rapidly progressive glomerulonephritis) and flat or saddle nose (due to a collapse of the nasal septum) is characteristic of granulomatosis with polyangiitis
28
Varencicline mechanism of action?
nicotinic receptor partial agonist
29
Buproprion mechanism of action?
norepinephrine and dopamine reuptake inhibitor, and nicotinic antagonist
30
ABG results for CO2 retainers?
ABG triad for chronic CO2 retention: - Normal pH - High pCO2 - High HCO3
31
Management of pneumothorax?
Primary pneumothorax Recommendations include: - if the rim of air is < 2cm and the patient is not short of breath then discharge should be considered otherwise, aspiration should be attempted - if this fails (defined as > 2 cm or still short of breath) then a chest drain should be inserted Secondary pneumothorax Recommendations include: - if the patient is > 50 years old and the rim of air is > 2cm and/or the patient is short of breath then a chest drain should be inserted. - otherwise aspiration should be attempted if the rim of air is between 1-2cm. If aspiration fails (i.e. pneumothorax is still greater then 1cm) a chest drain should be inserted. - All patients should be admitted for at least 24 hours if the pneumothorax is less the 1cm then the BTS guidelines suggest giving oxygen and admitting for 24 hours
32
Treatment of acute asthma exacerbation in primary care?
Course of 5 days prednisolone
33
What FEV1 (% of predicted) corresponds to what degree of COPD?
>80 - Mild (need Sx) 50-79% - Moderate 30-49% - Severe < 30% - Very severe
34
Is coal dust related to cancer risk?
No
35
Adverse effects of tetracyclines?
- discolouration of teeth: therefore should not be used in children < 12 years of age - photosensitivity - angioedema - black hairy tongue
36
What bacterium is associated with pneumonia in COPD pts?
Haemophilis influenzae