RESPIRATORY Flashcards

1
Q

**Acute Asthma Exacerbation

A

CF: Acute SO, Polyphonic wheeze, hyperinflated chest, mucous productionm increased HR + RR

PERF >50-70% moderate

Life threatening 33 92 CHEST
Perf <33, Sp02 < 92%, 
Cyanosis
Hypotension
Exhaustion
Silent chest
Tachycardia 
Management:
Oxygen 94-98% 15L NRB
Salbutamol Nebs hourly
Hydrocortisone /ORAL Pred 40mg 
Ipratropium Bromide Neb
Theopyline 
Magnesium consider
Escalate
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2
Q

**Acute Execerbation of COPD

Signs

Treatment

A

Signs: More coughing, wheezing, or shortness of breath than usual.
Changes in the color, thickness, or amount of mucus.

Treatment: 
COSI CCAR
Controlled Oxygen 28% Venturia
Salbutamol 5mg Neb
Ipratropium bromide 0.5mg
Chest X ray
Corticosteroids- Predinsolone 30mg or 200mg IV Hydrocortisone
Abx Amox + Doxy + Clarithromycin
Resp support Bipap 
Refer
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3
Q

** Hyperventilation panic attack

A
  • Its main effect is to lower pCO2 and produce a respiratory alkalosis.
    •Panic attacks must be associated with >1 month’s duration of subsequent, persisting anxiety about recurrence of the attacks, the consequences of the attacks, or significant behavioural changes associated with them

CF: SOB, pain in chest, paraesthisia, dizziness, perioral tingling, weakness, sweeting

IVX: ABG, ECG to exclude arrythmia

Management: Rebreathing in paper bag to build up pCO2- only when diagnosis certain
relaxation techniques, CBT, SSRI

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4
Q

**Acute Bronchitits

common age group?

CF
symptoms last?

Abx ?

A

Temporary Inflammation of the bronchi- commonly kids under 5 and often follows a cold
- CF: cough, fever, headache, coryzal, aches and pains
symptoms peak at 2-3 days but cough takes 2-3 weeks to go

Management: paracetemol, ibuprofen, hydration
Antibiotics for babies, >80 and complicated PMH
- Amoxicillin

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5
Q

** Tension Pneumothorax

A
  • One way valve with continual expanding pneumothorax into pleural space, no escape in expiration →mediastinum shifts to C/L hemithorax → compresses great veins → haemodynamic compromise → cardio-respiratory arrest

CF: Acute dyspnoea, Pleuritic chest pain, Haemoptysis
C/L Tracheal deviation, ↑HR, ↓BP, distended neck veins, dizzy, syncope + other signs stated earlier

NO CXR- treat before !!!!

Treatment:
Sit up, 02 15L NRBM, LARGE Bore needle decompression 2nd ICS midclavicular line
Attach Argyl Chest drain post decompression
- you know if its working if its swinging or bubbling

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6
Q

**Pneumonia

cause of CAP?

Syx:

signs:

CURB65 + scores mean?

Severe Abx treatment?

A

CAP most often strep pneumonia or haemophillus influenza
HAP = been in the last month for 2 days

CF: Fever, rigor, malaise, dyspnoea, cough with purulent sputum, haemoptyisis, pleuritic pain

Signs: Dull percussion and diminished expansion

IVX: CXR, ABG, Bloods, sputum, pleural aspiration for culture

Manage based on CURB-65

Confusion <8
Urea <7
RR <30
BP < 90/60
Age >65
Score 0-1 treat at home
2 hospital 
3 > severe pneumonia 

Severe:
02, treat hypotension IV fluids
Co-amoxiclav 1.2g/hr

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7
Q

** Pulmonary Embolus

RF major

CF

IVX

Score and what above indicates it is a PE?

ECG changes

Management:
Large
minor

A

Risk Factors: Major
Recent surgery, Pregnancy/ postpartum, lower limb problems, malignancy, reduced mobility

CF: Acute breathlessness, pleuritic chest pain, haemoptysis, syncope, hypotension, pyrexia, cyanosis, tachycardia, R ventricular heave, dizziness, Gallop Rhythm, DVT

IVX: Bloods D DIMER if low wells score! <4 points PE unlikely
ABG, CXR may be normal or show wedge shape,
ECG RBBB OR R Ventricular Strain
S1, Q3, T3 (inversion)
CTPA

Large: 02, Morphine, immediate thrombolysis
IV access Tinzaparin !!

Major + minor = LMWH HEPARIN with warfarin for 5 days + then WARFARIN for 3 months

Prevention: TED Stockings, stop OCP, if young test for
antiphospholipid. Thrombophillia

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8
Q

Asthma
CF

Diagnostic criteria

Adult stepwise management

A

CF: Atopy, noctural cough, dyspnoea, recurrent rhinitis, reflux, diurnal variation

Diagnosis:

a) Measure FeNO over ≥ 40
b) +ve Bronchodialtaory reversibility test: improvement post SABA of FEV1/FVC by ≥ 12% AND increase in volume of ≥ 200ml = +ve test

If uncertain of FeNO or Reversibility test, do Ponitor Peak Flow for 2-4 weeks

Adult Stepwise Management;

  • Go up ladder if using salb inhaler ≥ 3 doses a week
    1) SABA
    2) SABA + ICS
    3) SABA + ICS + LABA
    4) SABA + MEDIUM ICS or LTRA (remove LABA)
    5) refer to specialist
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9
Q

COPD
Pink puffer = emphysema
blue bloater = bronchiectasis

Spriometry readings

Management:

1) start
2) non asthmatic features
3) asthmatic features

Add on tx

A
  • Progressive, irreversible obstructive airway disease → chronic bronchitis (cough > 3 months, 2 consecutive years) and emphysema (enlarged alveolar air space)

CF: Productive cough, dyspnoea, polyphonic wheeze, accessory muscles,

IVX:

  1. Spirometry: <0.7, FEV1/FVC <70%
  2. CXR, FBC, BMI target 20-25, ABG,

GRADE of breathlessness 1-5
1 = not troubled, 5 = cant leave house

Management

  1. STOP SMOKING, refer
  2. Vaccination pneumococal + influenza
  3. Pulmonary rehabilitation
  4. Carbocysteine = mucolytic

1). OFFER SABA OR SAMA if need
2). If not asthmatic features –> LABA + LAMA –> then either LABA + LAMA + ICS or if really bad try 3 months but if no use- revert back to LABA and LAMA
3). If ASTHMATIC features –> LABA + ICS –> LAMA + LABA + ICS
Add theophylline if needed
Short term or long term 02 therapy
Rescue packs:
30mg PO Predinisolone 7 days post exacerbation
Abx: Amoxicillin
Bronchodialtor.

Complications: Cor pulmonale

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10
Q

Non-tension Pneumothorax

A
Primary = spontaneous (young, thin men) due to rupture of subpleural bulla 
Secondary = often >55yo, smoker, lung pathology on exam or CXR 

Pt. may be asymptomatic:
Acute or progressive dyspnoea
Pleuritic chest pain – worse on inspiration or coughing
Laboured breathing

Signs
no Tracheal deviation until tension
↓Expansion I/L
↑Resonance I/L 
↓Tactile fremitus I/L
↓Breath sounds; ↓Air entry; Pleural rub 
Cyanosis (severe), may have pyrexia

CXR: Hypodense area w/ loss of vascular markings

Management: 02 15L NRBM

  • Bore needle decompression 2nd ICS midclav if >2cm primary, 1-2cm secondary or Immediate chest drain if >2cm secondary
  • X-Ray to determine size post-decompression
  • If still large (<2cm primary, <1cm secondary) then Chest drain 5th ICS mid-ant axillary
  • Determine cause and treat accordingly
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11
Q

Pleural Effusion

CF

Signs

A

Can be Empyema (pus) Haemothorax, Chylothroax (lymph) or just fluid

CF: Dyspnoea on exertion, pleuritic chest pain, cough

Sign: STONY DULL PERCUSSION, reduced breath sounds on affected side, large effusion –> tracheal deviation

CXR: Small effusions blunt the costophrenic angles, larger ones are seen as water dense shadows with concave upper borders (MENISCUS)
–> Diagnostic aspiration AKA Thoracentesis

Management: Drainage – if effusion symptomatic or surgery if recurrent

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12
Q

Bronchial Carcinoma

A
Small cell (15%)
Rapidly growing and highly malignant = smokers

Non Small Cell

  • Squamous = central and local spread early
  • Adenocarcinoma = non-smokers “iduno” why i got it
  • Large cell = metastasie early

CF: weight loss, clubbing, cough, haemoptysis, chest pain, SOB

Sign: pleural effusion, consolidation

Urgent refer for CXR + 2 week wait
CT scan to stage tumour + cytology

Management: Excision, Chemo + radiotherapy

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13
Q

Lung Sarcoidosis

CF:

Management:

A

Multisystem chronic inflammatory condition characterised by the formation of non-caseating epithelioid granulomata at various sites in the body.

CF: Bilateral hilar lymphadenopathy, DRY cough, chest pain, decreased exercise tolerance

IVX: ESR, LFT, Ca increased

Stage CXR + tissue biopsy

Management: Steroids

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14
Q

Cystic fibrosis

A

•Autosomal recessive due to mutations in CFTR gene

CF: Meconium ileus in newborn – bowel atresia
Bronchiectasis, Pancreatic exocrine insufficiency, Raised Na sweat level, crackles, purulent sputum

IVX: sweat test, CXR

Management: Phsyio 3X day, antibiotics, vaccines

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15
Q

Inhailed foriegn body

how to treat infants
children
adults

A
  • If in the larynx, get croupy cough and stridor
  • If in bronchus (often R middle or lower lobe), no Sx for a few days until infection, collapse or obstructive emphysema develop

Severe obstruction: Unable to breathe or speak, wheeze, cyanosis

TX
Infants: 5 Back blow and 5 chest thrust
Children: 5 back blow and 5 abdo thust
Adult: 5 back slap and abdo trust- unconscious = CPR

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16
Q

Tuberculosis

when to suspect?

CF:

IVX

TB treatment - how many drugs?

A
  • Caused by Mycobacteroum tuberculosis
    Suspect if: Overseas contact, HIV +ve, Odd CXR

CF: Onset insidious
Primary infection usually asymptomatic
General Sx: Anorexia, Low fever, Failure to thrive, Malaise, Weight loss
Pulmonary: Cough is common (but may be absent) – chronic, productive with purulent +/- blood stained sputum, Lobar collapse

IVX: Tuberculin tests +CXR 
Management: Notifiable disease
RIPE
Rifampicin (worst one- causes aKI and deranges LFTs)
Isoniazid
Pyrazinamide
Ethambutol 

6 months- 4 drugs , Rifampicin, + 2 others

17
Q

Obstructive sleep apnoea

RF:

IVX- gold standard?

Management

A

•Intermittent and repeated upper airway collapse during sleep
Results in irregular breathing at night and excessive sleepiness during the day

RF: Obesity (strongest risk factor), Male gender, Middle age (55-59 in men, 60-64 in women), Smoking, Sedative drugs.

IVX: 5+ RESP events per hour
Polysomnography is gold standard

Mangement: Lifestyle, weight loss, CPAP

18
Q

(2) Empyema

A
  • Pocket of pus in pleural space
19
Q

(2) Lung abscess

A

Severe, localised suppurative infection in the substance of the lung, associated with necrotic cavity formation.

Syx: spiking temp and night sweats
• Cough ± phlegm production (frequently foul-tasting and foul-smelling and often blood-stained)

Management: anaglesia, o2, postural draiage and ABX

20
Q

(2) Mesothelioma

Caused by?

syx?

A

• Aggressive tumour of mesothelial cells which usually occurs in the pleura
(80-90% of all cases).
Rarely metastasises

Caused by asbestosis exposure

Syx: SOB, Chest pain
o	Dull, diffuse, progressive
o	Occ pleuritic 
•	Weight loss
•	Fatigue, fever, sweats
•	Finger clubbing
21
Q

(2) Coal workerks pneumoconoisis

syx

A
  • Caused by exposure to coal dust free of silica

syx: SOB, bring up black mucus, chest tightness

22
Q

(2) Bronchiectasis

A
  • Permanent dilatation and thickening of the airways characterised by chronic cough, excessive sputum production, bacterial colonisation, and recurrent acute infections
  • Diffuse or more localised

Cause: childhood infections, chronic resp disease

Management: Rx underlying cause but cant reverse damage

Lung trasnplant if <30% FEV1

23
Q

(2) Carbon monoxide poisoning

A

SYX:
Early: nausea, subjective weakness, headache and poor concentration/memory
Late: Neurological or neuropsychiatric features including disorientation, apathy, mutism, irritability, inability to concentrate, personality change, Parkinsonism and parietal lobe lesions.

IVX: Direct spectrophotometric measurement of HbCO in a blood gas analyser
• bedside HbCO oximeter is now available
• ABG – metabolic acidosis
• ECG – myocardial ischaemia or infarct

Management: oxygen 100%

Mannitol 1g/kg IV 20 minutes if cerebral oedema suspected

24
Q

COPD long term drug tx

A

1). OFFER SABA OR SAMA if need
2). If not asthmatic features –> LABA + LAMA –> then either LABA + LAMA + ICS or if really bad try 3 months but if no use- revert back to LABA and LAMA
3). If ASTHMATIC features –> LABA + ICS –> LAMA + LABA + ICS
Add theophylline if needed

25
Q

Idiopathic pulmonary fibrosis

Drug cthat can cause?

Treatment?

A

• Group of diseases which produce interstitial lung damage and ultimately fibrosis and loss of elasticity of the lungs = honeycomb appearance

Syx: dyspnoea, wheezing

Risk factors: AMIODARONE CAN CAUSE

Dust, animals, occupation (chemicals), smoking, GORD, autoimmune relations, infection

TX: Prednisolone + 02

26
Q

Croup treatment

A

DEXamethasone

27
Q

Sarcoidosis
- What do routine bloods show?
Key features?

A
  • Hypercalcaemia and a raised ESR

- Erythema nodosum, a non-productive cough, arthralgia and bilateral hilar lymphadenopathy on chest x-ray.

28
Q

Which lung cancers secrete ACTH + cause Cushing’s syndrome

A

Small cell lung carcinoma

29
Q

Which lung cancers secrete parathyroid hormone-related peptide which causes hypercalcaemia?

A

Squamous cell carcinoma

30
Q

Drug cause of pulmonary fibrosis

A

Amiodarone