Respiratory Physiology Flashcards

1
Q

What does Upper respiratory tract include?

A

Nose, Nasal cavity, mouth, pharynx, larynx

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2
Q

What does lower respiratory tract include?

A

Trachea, lungs, bronchi, bronchioles, alveolar ducts, alveolar sacs

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3
Q

Lung lobes left and right

A

Left 2 lobes

Right 3 lobes

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4
Q

Alveoli Type I & II cells function

A

Type I - continuous lining of alveolus- main site of gas exchange

Type II - secret surfactant (improves gas exchange)

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5
Q

Where are respiratory control centres found?

A

Within Brain 2 areas:

Pons -Apneustic Area, Pneumotaxic Area

Medulla rhythmicity area - Ventral & Dorsal Group

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6
Q

key Respiratory Nerves

A

Phrenic - C3-C5 root

Intercostal - T1-T11

Vagus - Cranial 10

Glossopharyngeal - Cranial 9

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7
Q

Receptors involved with respiration

A

Chemoreceptors

Mechanoreceptors (stretch)

Irritant receptors

Peripheral proprioceptors

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8
Q

Chemoreceptors different types

A

Central

Peripheral - carotid/aortic

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9
Q

Respiratory muscles

A

Accessory muscles

Diaphragm

Intercostal

Abdominal

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10
Q

What is boyle’s law?

A

Pressure of gas in a close container inversely proportional to column of container at constant temperature

P proportional 1/V

Volume ^ = Pressure down
Volume down = Pressure ^

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11
Q

Inhalation process

A

diagram flattens, intercoastal pull ribs out

volume ^ - pressure down = air flows in

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12
Q

Exhalation process (at rest)

A

passive process - elastic recoil

Elastin - found surrounding alveoli and recoil them following inflation

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13
Q

Exhalation process (active)

A

Abs, obliques, intercostals act together to force air out

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14
Q

Airflow / airway resistance equation

A

Pi x Pdiff x R4 / 8nL

R4 = radius power 4
8nL = 8 x viscosity x length
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15
Q

What does Apneustic region do?

A

Prolong and slow rate of breathing

overridden by pneumotaxic

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16
Q

What does Pneumotaxic region do?

A

Inhibitory impulse, limits duration

strong signal = ^ respiration rate

17
Q

What does medulla region (rhythmicity) do?

A

Dorsal respiratory group - inspiratory impulses

Ventral respiratory group - inspiratory and expiratory impulses (mainly active during exercise)

18
Q

What do central receptors do ?

A

Co2 diffuses in cerebral spinal fluid - disoates into H+ ions - central receptors detect signalling DRG & PNE

19
Q

What are the peripheral chemoreceptor called?

A

Glomus cells

20
Q

What do Glomus cells do?

A

Detect build up of potassium inside cell (K channels close without O2 (exercise))

Ca+ channels open Ca+ floods in releasing vesicles of dopamine