Respiratory - Sarcoidosis Flashcards
What is sarcoidosis?
Chronic granulomatous disorder
What is a granuloma?
Inflammatory nodule full of macrophages
Who is affected by sarcoidosis?
20-39 or 60
Women
Black
What is the typical presenting complaint of sarcoidosis?
Dry cough
Shortness of breath
Nodules on their shins
Black, 20-40 years old
What are the skin features of sarcoidosis?
Erythema nodosum
Lupus pernio
What is erythema nodosum?
Nodules of inflamed subcutaneous fat on the shins
What is lupus pernio?
Specific to sarcoidosis
Raised purple skin lesions on cheeks and nose
As sarcoidosis affects multiple organs why is it a respiratory issue?
Lungs are affected most commonly
What happens to the lungs in sarcoidosis?
Mediastinal lymphadenopathy
Pulmonary fibrosis
Pulmonary nodules
What are the systemic symptoms of sarcoidosis?
Fever
Fatigue
Weight loss
What happens to the liver in sarcoidosis?
Liver nodules
Cirrhosis
Cholestasis
What happens to the eyes in sarcoidosis?
Uveitis
Conjunctivitis
Optic neuritis
What happens to the heart in sarcoidosis?
Bundle branch block
Heart block
Myocardial muscle involvement
What happens to the kidneys in sarcoidosis?
Kidney stones
Nephrocalcinosis
Interstitial nephritis
What is Lofgren’s syndrome?
Classic triad of symptoms in sarcoidosis
- Erythema nodosum
- Bilateral hilar lymphadenopathy
- Polyarthralgia
