respiratory system Flashcards
(43 cards)
asthma definition
reversible airflow obstruction, problems with expiration
asthma pathological process
caused by narrowing of airway (smooth muscle constriction) caused by mucous secretion and bronchial mucosal oedema (inflammation)
asthma monitoring / tests
peak flow test = worse in mornings
test for airway obstruction
forced expiration rate = PV1
chest x-ray = visible fluid
skin prick test to exclude allergies
asthma treatment protocols
management of triggers
medications - bronchodilators (e.g. albuterol) or inhaled corticosteroids (e.g. fluticasone) to help reduce inflammation in the airways.
asthma action plan
regular follow up
assessing severity of asthma
ask about oral steroids and if there ever been hospital admission
physical examination
breathing tests
pyramid of drugs goes
SA B2 - LD inhaled - LA B2 - Others - Oral Steroid
asthma symptoms
cough, wheeze, shortness of breath
blue inhaler
intermittent SHORT acting beta-adrenergic agonists
RELIEVER
e.g. SALBUTAMOL, TERBUTALINE
relaxes bronchial smooth muscle
○ Reduce bronchoconstriction
○ Reduce resting bronchial tone
protective against stimuli – take in anticipation of need; exercise induced asthma
quick onset
can be given inhaled, oral, IV
brown inhalers
inhaled Corticosteroids – low and high dose
ANTI-INFLAMMATORY
E.G. BECLOMETHASONE
BUDESONIDE
reduces mucous secretion and mediators that trigger contraction of bronchial smooth muscle
use if Short acting β2 agonist >3 times each week then use LOW DOSE inhaled corticosteroid every day
move to HIGH DOSE inhaled corticosteroid if symptoms dictate
spacer recommended
PREVENTION, NOT DURING ACUTE
green inhaler
intermittent LONG acting beta-adrenergic agonists
PREVENTION
E.G. SALMETEROL
relaxes bronchial smooth muscle
○ Reduce bronchoconstriction
○ Reduce resting bronchial tone
slow on set
ALWAYS USED WITH INHALED STEROID
asthma attack in the chair
make sure if pt have attack in the chair, they are monitored in the future
even though they seem to improve, give them corticosteroids in a&e (brown inhaler)
give oxygen
drugs that impair ventilation
beta-blockers - make them narrower
aspirin
respiratory depressants:
benzodiazepines (diazepam) = causes bronchial spasm
opioids (oxycodone, morphine, hydrocodone)
drug used to improve gas exchange
oxygen
inhaled respiratory drug delivery methods
meter Dose Inhaler MDI - “Puffer”
breath Activated Device
○ Spinhaler
○ Turbohaler
aids to respiratory drug delivery
nebuliser and spacer
grey inhaler
anticholinergic
inhibits muscarinic nerve transmission in autonomic nerves
HELPS TO OPEN AIRWAY
additive to B agonists
E.G IMPRATROPIUM
asthma pill drugs
mast cell stabilisers
leukotriene inhibitors
biological medicines
oxygen
standard relievers of asthma in dentistry
blue salbutamol and oxygen
copd causes
smoking, inherited, asthma, air pollutants, AAT deficiency (alpha-1 antitrypsin)
copd components
asthma component – reversible (ish)
bronchiectasis & emphysema (destruction of alveoli) component - non-reversible
copd treatment
- Smoking Cessation
- Long acting Bronchodilator (green inhaler)
- Combined with Inhaled Steroids? (<50% FEV)
- (systemic steroids)
- Oxygen Support
- Pulmonary rehabilitation therapy
copd acute episode
a sudden worsening of symptoms in a patient with COPD.
it is typically characterised by an increase in coughing, wheezing, shortness of breath, and chest tightness.
treatment : oxygen therapy, blue inhaler, corticosteroids, antibiotics, non-invasive ventilation
copd chronic type
Alveolar effects - Type 1 (hypoxia) - PINK
* reduced surface area for gas exchange
* thickening of alveolar mucosal barrier
* Often hyperventilate to compensate (pink puffer)
Poor ventilation - Type 2 (CO2 retention and hypoxia) - BLUE
* airway narrowing (reversible?)
* restrictive lung defects
* No good gas control
what is copd
MIXED airway reversible obstruction and destructive lung disease
It separates from asthma that is reversible
type 1 copd
enough O2 but can’t diffuse it