Respiratory System & Physiology Flashcards

Components, Inhalation/Exhalation & Control of Breathing

1
Q

Role of the respiratory system

A

To intake Oxygen (required by the body for respiration) and remove unwanted gaseous waste products (Carbon Dioxide).

This process is also known as gas exchange.

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2
Q

What is the thoracic cavity?

A

The space in the body where the lungs are

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3
Q

Lungs

A

Two in each human contain bronchi, bronchioles and alveoli.

Have a light, spongy texture as they contain a large proportion ofgases (used for gas exchange).

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4
Q

What is the pathway of air INTO the body?

A

Mouth (Buccal/ Oral Cavity)
Trachea (windpipe)
Bronchi
Bronchioles
Alveoli
Bloodstream (cappilaries)

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5
Q

What is the difference between the trachea, bronchi & bronchioles?

A

The trachea is the windpipe found at the end of the mouth (and rinds down the neck).
This then branches off into two bronchi, one of which goes in each lung.
The bronchi then branch off into many bronchioles, the alveoli are found at the very end of the bronchioles.

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6
Q

Cartilage in the airways

A

Strong and flexible rings of cartilage surround the airways.
This helps to hold the airways open (during inhalation)

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7
Q

Ciliated epithelia

A

Found in the inner surface of the trachea and bronchi.
They waft mucus produced by goblet cells out of the airways (into the oesophagus)

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8
Q

What happens during inhalation?

A

The diaphragm contracts and flattens and external intercostal muscles contract. This causes the volume of the thoracic cavity to increase

Pressure in the lungs is reduced (to lower than the atmosphere), therefore air is forced into the lungs down a pressure gradient.

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9
Q

What happens during exhalation?

A

The diaphragm relaxes and domes up and the external intercostal muscles relax. This causes the volume of the thoracic cavity to decrease.

Pressure in the lungs is increased above the atmosphere and air is forced out of the lungs down a pressure gradient.

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10
Q

What happens during forced exhalation?

A

The diaphragm relaxes and domes back up, the internal intercostal muscles contract, pulling the ribs down and in. This causes the volume of the thoracic cavity to decrease.
Pressure increases above the atmosphere and moves out, down its concentration gradient.

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11
Q

Control of Breathing (increase)

A

Breathing rate is increased when high levels of carbon dioxide are detected in the blood.
Nerve impulses from the brain are sent to internal intercostal muscles and the diaphragm to increase contractions and therefore the breathing rate

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12
Q

Control of Breathing (decrease)

A

Stretch receptors (in the wall of the alveoli) detect an increased volume of blood so the breathing rate needs to decrease.
Nerve impulses are sent from the brain to internal intercostal muscles and the diaphragm to decrease contractions and therefore the breathing rate.

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13
Q

What are the alveoli?

A

Microscopic sacks, which is where gas is exchanged (in and out) between the blood and the bronchioles/air
There are millions of alveoli in each lung.

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14
Q

Pulmonnary Surfactant

A

Fluid secreted by the alveoli which helps to reduce surface attention of the pulmonary fluids and prevent the alveoli from collapsing during expiration

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15
Q

Pathway of air INTO capillaries (alveoli)

A

Alveolar Space
Alveolar epithelium
Capillary endothelium
Capillaries (blood)

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16
Q

Adaptations of the Alveoli

A

They have a thin exchange surface (one cell thick) to provide a short diffusion pathway to speed up the rate of diffusion.

They have a large SA (as there’s many of them) to provide a faster rate of diffusion.

There is a good blood supply which provides a steep concentration gradient of oxygen and carbon dioxide. This helps to increase the rate of diffusion as it relies on different in concentration.

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17
Q

Capillary (lumen) in relation to gas exchange

A

The lumen of the capillary only allows one red blood cell to pass through at a time.
This helps to drastically decrease the pressure and the speed of blood flow which allows for gas (and ion) exchange to take place more efficiently.

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18
Q

What is the diaphragm?

A

A dome shaped sheet of muscle found under the lungs

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19
Q

Role of the diaphragm

A

During inspiration, the diaphragm muscles contract and flatten, to increase the space in the thoracic cavity (to allow more gas to move into the lungs).

During expiration, the diaphragm muscles relax and cause the diaphragm to curve again this decreases the space in the thoracic cavity to force more air out of the lungs.

20
Q

Ribs

A

The ribs are curved, flat bones arranged to form a cage like structure around the lungs which helps to protect them (and other organs)

21
Q

External Intercostal muscles in relation to the ribs

A

Contract during inhalation to push the ribs upwards and out to maximise the size of the thoracic cavity.

Relax during exhalation the ribs fall causing the size of the thoracic cavity to decrease.

22
Q

Internal Intercostal muscles in relation to the ribs

A

Contract during forced exhalation to force the ribs inwards and downwards
therefore decrease the size of the thoracic cavity

23
Q

What are the pleural membranes?

A

A thin layer of tissue which covers each lung and secretes a lubricating fluid

24
Q

Role of the pleural membranes

A

They secrete a lubricating fluid which allows the lungs to inflate and deflate without rubbing against the rib cage (and causing damage)

25
Q

Asthma

A

A long disease which causes the airways in the body to build up with mucus, therefore restricting the amount of oxygen which can enter the blood

26
Q

Asthma- Causes

A

Genetics
Pollution
Smoking
Dust
Pets/Perfumes

27
Q

Asthma- Treatments

A

An inhaler which helps to reduce mucus build up and therefore keep the airways open

Less intensive exercise

28
Q

Causes of lung cancer

A

Smoking (including passive)
Radon gas
Pollution
Occupational exposure

29
Q

Symptoms of lung cancer

A

Breathlessness
persistent cough
chest infections
pain when coughing
coughing up blood
loss of appetite
weight loss

30
Q

Treating lung cancer

A

surgery
radiotherapy
chemotherapy

31
Q

Bronchitis

A

The inflammation of the airways in the lungs, caused by:
viruses
bacteria
irritant substances
occupational exposure

32
Q

Symptoms of bronchitis

A

Cough
phlegm
sore throat
headache
runny/blocked nose
tiredness
aches & pains

33
Q

Treating bronchitis

A

rest
stop smoking
anti inflammatory drugs

34
Q

Emphysema

A

A disease which causes the gradual damage of lung tissue, specifically alveoli sacs leading to a lower gas exchange surface (and rate)

35
Q

Causes of emphysema

A

smoking
fumes or dust at work
air pollution
genetics

36
Q

Symptoms of emphysema

A

breathlessness
persistent chesty cough
chest infections
swollen ankles
weight loss

37
Q

Treating emphysema

A

stop smoking
lung transplant
medication
inhalers or surgery
pulmonary rehabilitation (exercise & education)

38
Q

Pulse oximeter

A

A device placed onto the fingertips which measures oxygen saturation in the blood (healthy is 95-100%)

39
Q

Limitation of pulse oximeter

A

Results are not as accurate as taking a blood sample, especially for below 80%

40
Q

Peak expiratory flow

A

A tests which measures the maximum exhalation rate using a peak flow meter. The test is repeated 3 times and the highest score is recorded.

41
Q

Using a peak flow meter

A

The test may be carried out either sitting or standing (but must always be the same)
Push the pointer down to 0.
Hold the peak flow meter horizontally.
Take a deep breath in and place the mouthpiece between the patients’ lips.
Ask the patient to breathe out as deeply as they can and record this result (indicated by where the pointer is)

42
Q

What are peak flow meters used for?

A

To monitor asthma patients, and can be used to indicate how narrow airways are in the body before and after treatments.

43
Q

Spirometer measures

A

Forced expiratory volume (per second)

forced capacity (total amount of air blown out in one breath)

Slow vital capacity (how much air is blown out whilst relaxed)

44
Q

How to use a spirometer

A

Test taken seated
A clip is placed on nose and a plastic mouth piece is given
Lips are pressed around the mouth piece and the patient is asked to breath in as big and deep as possible before exhaling as fast as possible
Results are provided as a graph
Results are given as a graph

45
Q

Limitations of spirometer & peak flow

A

Patient error when using equipment (e.g. not breathing hard enough, not sealing lips properly etc..)