respiratory tract infections Flashcards

(34 cards)

1
Q

What are some URTI’s

A

coryza (common cold), pharyngitis, sinusitis, epiglottis, diphtheria

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2
Q

what are some LRTI’s

A

acute bronchitis, pneumonia, influenza

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3
Q

describe epiglottis and how to treat it

A

inflammation of the epiglottis, can obstruct airway and be life threatening, especially in children, endotracheal intubation and IV antibiotics

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4
Q

describe diphtheria

A

white-grey coating at back of mouth with other symptoms of infection. rare in UK but can be life-threatening due to toxin production

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5
Q

describe acute bronchitis

A

usually with COPD patients wheeze, productive cough and fever, usually self limiting, normal CXR and lung sounds, no antibiotics unless needed

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6
Q

which 4 viruses mainly cause common cold

A

adenovirus, rhinovirus, coronavirus

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7
Q

how does sinusitis present

A

runny nose, frontal lobal headache

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8
Q

who most commonly gets bronchiolitis and what are the symptoms

A

babies, coryza with fever, cough and wheeze, resp sinus virus (RSV)

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9
Q

what are the complications of bronchiolitis

A

respiratory and cardiac failure

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10
Q

what are the 4 main chronic RTI’s

A

intrapulmonary abscess, empyema, bronchiectasis (chronic bronchial sepsis), cystic fibrosis

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11
Q

what can cause chronic infections

A

immunodeficiency and immunosuppression, abnormal innate defence (damaged bronchial mucosa) and repeated insult (recurrent infection)

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12
Q

what can cause immunodeficiency

A

CVID, no lymphocytes (protected up to 3 months from IgG), Di George (no thymus T cells, hypogammaglobulin (No B), hyposplenism, HIV, cancer

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13
Q

what causes immunosuppression

A

mainly drugs eg steroids, chemo, azathioprine

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14
Q

what causes innate defence

A

damaged bronchial mucosa from smoking, pneumonia, malignancy etc, abnormal cilia (kotsmanns and youngs), abnormal secretions (CF)

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15
Q

what causes repeated insult

A

recurrent aspiration eg NG tubes

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16
Q

what are the symptoms of an intrapulmonary abscess and what is it

A

liquefactive necrosis –> cavities weight loss, lethargy, cough +/- sputum

17
Q

what can cause intrapulmonary abscess, how do you identify it, how do you treat it

A

bacteria eg strep and staph, fungi eg aspirgillis, septic emboli, pneumonia, CT = orange, AB’s if needed

18
Q

what is empyema

A

pus in pleural cavity

19
Q

what can cause empyema

A

aerobic most frequent - pseudomans, strep milleri, staph A, e. coli, legionella

20
Q

what is the diagnosis of empyema

A

USS best, CT, D sign on chest xray

21
Q

what is the treatment for empyema

A

IV (amoxicillin, metronidazole), large effusion drain chest

22
Q

what is bronchiectasis

A

irreversibly widened airways that can collapse easily and cause obstruction. often cause crackles and abnormal cilia

23
Q

what can cause bronchiectasis

24
Q

what are the symptoms of bronchiectasis

A

recurrent chest infections, cough + sputum, chest crackles and pain

25
what investigations are done for bronchiectasis
CT, hard to diagnose
26
what is the treatment for persistent bronchiectasis
ceftazimide
27
what is chronic bronchial sepsis
symptoms of bronchiectasis but no radiology results, positive sputum culture
28
what is cystic fibrosis
autosomal recessive disorder that can causes over-secretion and can lead to a failure to thrive. often low life expectancy
29
what is the brief mechanism of CF
CFTR defective, chlorine not pumped out of cell and builds up, sodium follows it causing dehydration and thick mucous. this blocks ducts and impairs mucosal defence causing infections and inflammation
30
how many people carry CF
1/25
31
where is the CF mutation
G55TD gene of chromosome 7, Del508 inheritance
32
what are the symptoms of CF
cough, infections, crackles, low BMI, trouble breathing, salty sweat - sweat test. is the main cause of bronchiectasis
33
what treatments are available with CF
lifelong and lots of antibiotics, physiotherapy, OPHAT
34
what is the problem with CF drugs
very expensive and not curative