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PHRM 844 > Review > Flashcards

Review Flashcards

1
Q

most important labs in thyroid

A

free t4 and TSH

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2
Q

hyperthyroidism labs

A

low TSH
high T4

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3
Q

hypothyroidism labs

A

low T4
high TSH

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4
Q

compounds that have iodine

A

Amiodarone, lithium

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5
Q

hyperthyroidism treatment

A

thioamides: methimazole and propylthiouracil

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6
Q

methimazole dosing

A

free t4 1-1.5 ULN 5-10 mg
1.5-2 ULN 10-20 mg
2+ ULN 30-40 mg

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7
Q

thioamides adverse effects

A

GI, rash, agranulocytosis (fever,flu, immune), hepatitis

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8
Q

what to use in hyperthyroid patients with HR over 90

A

beta blockers
(prefer metoprolol and atenolol)

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9
Q

hypothyroidism drugs

A

levothyroxine, liothyronine, armour thyroid

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10
Q

black box warning levothyroxine

A

weight loss

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11
Q

counseling for levothyroxine

A

60 mins before breakfast or 4 hours after dinner
empty stomach

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12
Q

uncomplicated adult levothyroxine dosing

A

1.6 mcg/kg/day

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13
Q

elderly thyroid dose

A

start 25-50 mcg / day

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14
Q

cvd thyroid dose

A

12.5-25 mcg/ day

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15
Q

pregnant pts thyroid dose

A

45% increase in dose

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16
Q

drug interactions
levothyroxine

A

antacids, bile acid, calcium, warfarin

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17
Q

GERD alarm sx

A

dysphasia
odynophagia
bleeding
weight loss

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18
Q

when to refer GERD

A

alarm sx or no PPI relief after 14 days

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19
Q

side effects of calcium

A

constipation

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20
Q

side effects magnesium

A

diarrhea

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21
Q

side effects aluminum

A

constipation

22
Q

antacids counseling
w

A

take meds 2 hours before or 4-6 hours after antacids

23
Q

H2RA mechanism

A

reversible inhibition of histamine receptors

24
Q

H2RA pearls

A

beers
tachycardia
delirium
good for nocturnal

25
Q

H2RA with side effects

A

cimetidine

26
Q

PPis MOA

A

irreversible inhibition of proton pump

27
Q

PPis with meals

A

30-60 mins before meal

28
Q

pregnancy w gerd agents preferred

A

antacids or sucralfate
H2ra second line

29
Q

which agent should be avoided in kids

A

bismuth subsalicylate

30
Q

ulcer in duodenum

A

pain relieves with food

31
Q

ulcer in stomach

A

worsens with food

32
Q

h pylori tx principle

A

PPI and 2-3 antibiotics

33
Q

bismuth quad

A

PPI BID
bismuth subsaliclate
metronidazole
tetracycline
10-14 days

34
Q

alternative to bismuth quad

A

PPI BID
levofloxacin 500 mg
amoxicillin 1 g BId

35
Q

prophylaxis NSAID induced ulcer drug

A

misoprostol

36
Q

treatment only drug NSAID induced ulcer

A

sucralfate

37
Q

NSAID induced ulcer treatment time

A

8 weeks if NSAID stopped
12 weeks if continued

38
Q

post of n/v risk factors

A

female
non smoker
history motion sickness
history post op nv

39
Q

loperamide dosing

A

4 mg initially then 2 mg after each loose stool
max 16 mg / day

40
Q

constipation when to refer

A

2 weeks sx
black stool
abe pain
fever

41
Q

bulk laxatives

A

psyllium
softens stools better than docusate

42
Q

surfactant

A

docusate
not effective for active constipation

43
Q

hyperosmotic

A

glycerin suppository and miralax
good for chronic constipation

44
Q

stimulant laxatives

A

senna and bisacodyl
good for opioid induced constipation

45
Q

hip and knee tx osteoarthritis

A

acetaminophen 4 g per day

46
Q

hand tx osteoarthritis

A

oral NSAID

47
Q

osteopenia t score

A

-1.1 to -2.4

48
Q

osteoporosis t score

A

<2.5

49
Q

bisphosphonates counseling

A

take on empty stomach
full glasss of water
do not lie down for at least 30 mins
do not chew

50
Q

serms can be used for

A

back

51
Q

raloxifine black box

A

risk vte or stroke

52
Q

denosumab risk

A

rebound risk fracture after discontinuing
hypoclcemia

PHRM 844 (16 decks)

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