Review Flashcards

(64 cards)

1
Q

What determines what different tissues get different hormones from cholesterol

A

enzymes

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2
Q

What is the difference between steroid and protein hormone storage

A

Steroid-not stored

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3
Q

What is tyrosine

A

Hormone that gives rise to T3/4 and catecholamines and dopamine

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4
Q

Where do steroid receptors function

A

in the nucleus/in the cell

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5
Q

where are protein hormone receptors

A

on the surface

2nd messenger system

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6
Q

What does TRH do

A

increase TSH increase thyroid

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7
Q

what does CRH do

A

increase ACTH

increase adrenal cortex hormones

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8
Q

What does GnRH do

A

increase FSH/LH

increase ovary/testies hormones

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9
Q

What does the hypothalamus do

A

Produce hormones that travel to the pituitary

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10
Q

What are the two hormones released from neurohypophisis

A

ADH and oxytocin

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11
Q

what makes ADH and oxytocin unique

A

made in one place, secreted in another

conserved among species

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12
Q

What does prolactin do

A

drive milk production from alveolar cells

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13
Q

what does oxytocin do

A

milk let down

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14
Q

What are glycoprotein hormones

A

FSH, LH, TSH

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15
Q

What’s the difference between the a and b subunit in glycoproteins

A

A is common

B is specific

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16
Q

What happens when there is deficiency in GH

A

pituitary dwarfism

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17
Q

Is GH deficiency/excess different depending on when the deficiency/excess occurs

A

yes

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18
Q

What is IGF-1

A

mediator for effects of growth hormone

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19
Q

What are the two major organs responsible for handling stress

A

Adrenal medulla/cortex

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20
Q

Why is epinephrine the major catecholamine

A

there is more of it than norepinephrine

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21
Q

how is thyroid hormone secretion regulated

A

Negative feedback between T3/4 from the thyroid on TRH from hypothalamus and TSH from anterior pituitary

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22
Q

What are major effects of thyroid hormone

A

increase major overall metabolic rate
Growth in young animals
Development and maturation of the CNS

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23
Q

Primary hypothyroidism

A

Thyroid produces less T4

95% fo cases in dogs

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24
Q

Secondary Hypothyroidism

A

abnormality at pituitary level

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25
Tertiary hypothyroidism
abnormality at hypothalamus
26
Cretinisim
developmental hypothyroidism
27
Where is hyperthyroidism most common
older cats
28
What are treatments of hyperthyroidism
Surgical removal anti-thyroid drugs (methimizole) Radioiodine
29
What are the two major types of diabetes
insulin dependent | insulin independent
30
Which type of diabetes is more common in dogs and how do you treat all dogs with diabetes
IDDM | Insulin
31
What disease is one of the few that you see in young dogs
hypothyroidism
32
What are some characteristics of diabetes in the cat
treatments vary (insulin or drugs) NIDDM and IDDM 1/3 of cats are NIDDM
33
Is the adrenal cortex and medulla regulated the same way
no
34
What is the renal control of the outer zone (zona glomerulosa)
Renin/angiotensin/aldosterone system
35
What is the control system of the inner zone of the adrenal gland (zona fasiculata/recticularis)
ACTH/Cortisol
36
How are glucocorticoids produced
CRH from hypothalamus ACTH form pituitary Glucocorticoids from adrenals Glucocorticoid has negative feed back on CRH and ACTH
37
What animals produce only cortisol
Cats, primates, livestock, other mammals
38
What animal uses both cortisol and corticosterone
dogs
39
what animals only make corticosterone
birds, rats, mice, penguins
40
Characteristics of hyperadrenocorticism
Cushing common in dogs spontaneous and iatrogenic
41
What causes spontaneous cushings
excessive ACTH production (PDH) | most common cause
42
How do you diagnose Cushing
Clinical symptoms Elevated cortisol ACTH challenge low dose DEX test
43
What happens if you give a high dose of DEX
PDH suppressed | Tumor not suppressed
44
What are levels of ACTH with primary and secondary Cushings
Primary=high | secondary=low
45
What does PTH do
increase serum Ca levels
46
Primary hyperparathyroidism
High PTH | High Ca
47
Secondary hyperparathyroidism
high PTH | deceased CA levels
48
Hypervitaminosis D
Suppressed PTH | High Ca
49
Hypercalcemia of malignancy
same as hypervitaminoisis D
50
What do Wolffian ducts develop into
Male repro
51
What does Mullerian Duct develop into
female repro
52
What does GnRH stimulate
LH FSH
53
What do GnRH, FSH, and LH have in common with release
pulsatile
54
What does LH do
stimulates leyding cells
55
What do thecal cells and granulosa cells work together to produce
Estridiol
56
what are animals that are induced ovulators
cats rabbits
57
What are steroid hormones derived from
cholesterol
58
What could happen when iatrogenic hyperchorticoid treatment is abruptly stopped
Iatrogenic hypochorticoid
59
Where is somatistatin and what is it
Growth hormone inhibiting hormone | Hypothalamus
60
What does LH act on in the female
Theca cells
61
What is produced in adrenal medula
Epinephrine
62
What are the 2 main questions of endocrine
What happens if you take a hormone away | What happens if you add extra of a hormone
63
How many steroids are made in Hypothalmus
none
64
What does a steroid have to bind to in the nucleus
steroid receptor