Revision 2

Question 1

Most important antigen presenting cell is

Answer 1

Dendritic cell

Question 2

Which immune receptor acts through inflammasome ?

Answer 2

Nod like receptors

Question 3

Following receptors are a/w-
1. TLR 1
2. TLR2- 
3.TLR3
4/ TLR4
5. TLR9

Answer 3

1. TB
2. GRAM +ve
3. Viral RNA
4. Gram -ve
5. Flagella
6. . bacterial DNA, Herpes, malarial parasite

Question 4

In each of following pathway what acts as C3 convertase ?

1. Classical pathway
2. Lectin pathway
3. Alternate pathway

Answer 4

1. C4b2a
2. C4b2a
3. C3bBb

Question 5

Eg of cytosolic immune receptor ?

Answer 5

Nod like receptors (NLR)

Rig like receptor (RLR)

Question 6

Function of MHC III ?

Answer 6

Encodes TNF, lymphotoxin, complement protein

Question 7

Positive tuberculin test is an example of which type of hypersensitivity ?

Answer 7

IV

Question 8

Causal agent behind m/c cancer in AIDS ?

Answer 8

HHV 8 causes Kaposi sarcoma ( a vascular neoplasm)

Question 9

Intermediate filament which makes up Mallory bodies in hepatocytes ?

Answer 9

Keratin

Question 10

Diagnostic standard for amyloidosis

Answer 10

Abdominal fat staining

Question 11

Type of spleen seen in amyloidosis

Answer 11

Lardaceous spleen

Question 12

Which part of spleen is involved in
Lardaceous spleen
Sago spleen

Answer 12

Red pulp

White pulp

Question 13

Difference b/w Werner and Wermer syndrome ?

Answer 13

Werner- premature aging

Wermer- MEN I syndrome

Question 14

Eg of
Endogenous pyrogens
Exogenous pyrogens

Answer 14

Endogenous- IL 1

Exogenous- LPS in bacterial wall

Question 15

Which cell shows MHC I & MHC II respectively

Answer 15

MHC I- all nucleated cells and platelets

MHC II- dendritic cells, B- cells, lymphocytes

Question 16

What is trousseau syndrome ?

Answer 16

Migratory thrombophlebitis seen in many GIT, haematological malignancies

Question 17

Parasites implicated in pathogenesis of cholangiocarcinoma-

Answer 17

Ophisthorchis viverrini

Clonorchis

Question 18

P53 is located on chromosome-

Answer 18

17

Question 19

Chromosome for HLA

Answer 19

6

Question 20

Tissue factor binds and activates

Answer 20

Factor VII

Question 21

Red infarct is seen in-

Answer 21

Testes

Lungs small intestine

Question 22

White infarct is seen in

Answer 22

Spleen

Question 23

Are the neutrophils in NETs alive ?

Answer 23

No they. Lose their DNA and die

Question 24

What is metastatic Crohn’s disease ?

Answer 24

Skin lesions inn Crohn’s disease , in the form of cutaneous granuloma s.

Question 25

Leventhal colle Lille bodies are seen in

Answer 25

Psittacosis