Revision Med Year 1 Flashcards
(52 cards)
Tetrahedral hybridisation
Sp3
Planar hybridisation
Sp2
Linear hybridisation
Sp
Hydrogen hybridisation and shape
s & sphere
What is the hybridisation of benzene
sp2
How many sigma and pi bonds are in a double bond
1 sigma
1 pi
How many sigma and pi bonds are in a triple bond
1 sigma and 2 pi
Which orbital overlap create a pi bond
P orbitals
Write down the confirmations of butane from most to least stable
Anti-staggered
Gauche staggered
Eclipse
Syn eclipsed
What does E and Z mean
E - enemies so opp sides
Z- ze same side
Equation for calculating specific optical rotation
[a] = a/cl
concentration = g/ml Length = dm
1dm = 10cm
How to calculate number of stereoisomers?
2 to the power of number of chiral centres
What is a meso compound?
A compound which contains a chiral centre but is superimposible on its own image
What is the level of sodium in the body?
4 moles
What is the level of sodium in serum
140mM
What is the level of potassium in the cells?
150mM
What is the serum level of potassium?
4-5mM
What is lithium carbonate used for as a drug?
Treats bipolar disorder and depression because reduces suicidal risk
Which drugs can chelate calcium
Tetracyclines and quinolones
What is the role of calcium as a drug?
Used to treat hypertension and angina
What is magnesium carbonate used for as a drug
Indigestion
Where is strontium used in?
In sensitivity toothpaste we have strontium chloride
Which element is found in vitamin B12?
Cobalt
Which enzyme is zinc found in?
ACE - angiotensin concerting enzyme