Revison Patient Flashcards

1
Q

Function of nucleus

A

Control the activity of the cell and contains genetic material/DNA

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2
Q

Structure and function of golgi

A

Stack of flattened membrane sacs

Modifies and packages proteins

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3
Q

Structure and function of mitochondria

A

Bean shaped organelle

Site of aerobic respiration for the production of ATP via oxidative phosphorylation

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4
Q

Structure and function of ER

A

Tubes and channels
Synthesis’s proteins and lipids
Detoxify drugs, folds and transports proteins

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5
Q

Structure and function of lysosome

A

Membrane bound organelle

Contains digestive enzymes for opoptosis

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6
Q

Functions of cytoskeleton

A

Contain proteins like actin, microfilaments and microtubules

Holds and helps the cell to move

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7
Q

How does cholesterol help the membrane

A

It provides more flexibility for the membrane to be tightly packed

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8
Q

Example of endocytosis reaction

A

Phagocytosis

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9
Q

Define active transport

A

Against concentration gradient
Requires ATP
Uses specific carrier proteins

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10
Q

Difference between channel and carrier proteins

HINT: carrier = enzyme

A

Channel proteins are water filled pores and allow ions to pass through

Carrier proteins bind a specific solute and then undergo a conformational change

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11
Q

Give an example for a drug which block ABC transporters

A

Digitalis

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12
Q

Which gene is affected in cystic fibrosis

A

Deletion of phenylalanine on chromosome 7 gene CFTR

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13
Q

Name an antibiotic that affects the P site

A

Chloramphenical

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14
Q

Name an antibiotic that affects the A site in bacteria

A

Tetracyclines

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15
Q

Name a drug that affects the E site if bacteria

A

Erythromycin

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16
Q

Do prokaryotes and eukaryotes have the same ribosomes?

A

No

17
Q

How to calculate number of peptide bonds

A

Number of amino acids - 1

18
Q

Equation for % ionisation of an acid

A

100 / 1 + antilog (pH-pKa)

19
Q

Equation for % ionisation of a bass

A

100 / 1+ antilog (pKa-pH)

20
Q

How to calculate isoelectric point

A

PKa of acid + pKa of base / 2

21
Q

Name the 2 amino acid helix breakers

A

Glycine and proline

22
Q

Why do beta sheets appear pleated

A

Because carbon is tetrahedral and peptide bond is planar

23
Q

What are the forces holding secondary structure called

A

Hydrogen bonding