rheum Flashcards
(56 cards)
what arthristis is associated with a rash on palms and soles and whats it called
reactive arthritis
keratoderma blenorrhagica
how is a dexaethasone suppression test done in cushings
dex given at 10pm and measured in morning
treatment of methotrexate toxicity
folinic acid
what things do the spondyloarthropothhies have in common
inflammatory arthritis
dactlyitis
enthesis
sacroiliac/ spinal involvement
is azathioprine safe in pregnancy
yes
how often is methotrexate taken
weekly
what antibiody is assoc with diffuse systemic sclerosis
anti-scl 70
what test should be done before starting biologics in Rheumatoid arthirtis and why
CXR to check. for Tb as may reactivate
methotrexate should not be prescribes alongside what antbiotic and why
trimethoprim - may cause bone marrow suppression and severe pancytopeania
what is side effecct of sulfasalazine
steven johnson syndorme
oligospermia
pneumonitis
myelosuppression
colouring of tears - staining contact lenses
how should bisphosphonates be taken and why
Oral bisphosphonates should be swallowed with plenty of water while sitting or standing on an empty stomach at least 30 minutes before breakfast (or another oral medication); the patient should stand or sit upright for at least 30 minutes after taking
if they sit in oesophagus they cause oesophagitis
whats the most specific test for SLE
ANti dsDNA
whats a good rule out test for lupus
ANA - 99% specific
what baseline test should be doen before staarting hydroxychloroquine
pthalmologist exam as causes bull’s eye retinopathy - may result in severe and permanent visual loss
eye complication of tamporal arteritis
anterior ischaemic optic neuropathy
what is feltys syndrome
RA- spenomegaly and low WCC
most common septic arthirits organism over all? in adults? where does it come from ie how does it spread to joint
staph aureus
gonorrhoea in young adults
haematogenous spread
when should bisphosphonates be strated in osteoporsis
Offer prophylactic bisphosphonates to those with a T-score < -1.5 if they are on steroids / going to be on steroids for 3 or more months (even if <65 years-old)
what sntbody seen in limited systemic sclerosis- where on body is sclerosis seen
anti-centromere - distal arms and legs
duration of antibiotic course in septic arthritis
4-6 weeks
first lien investigation in coeliac. what additional things can be tested for
what is gold standard
Anti-TTG antibodies (IgA)
others = endomyseal antibody (IgA)
anti-gliadin antibody (IgA or IgG)
anti-casein antibodies
gold standard = endoscopic intesinal biopsy
- what do carcinoid tumours secrete
- investigation and treatment of carcinoid tumour
serotonin (sometimes ACTH and GnRH)
urinary 5-NIAA
octreotide
what kind of antibody is RF
what kind of antibodies are hep A, B and C
IgM
Hep A -IgM
Hep B- IgM
Hep C - IgG
what test detects RF
rose waater test
