Rheumatic Lecture Flashcards
(31 cards)
Rheumatic disease - inflammatory process
When you get inflammatory rheumatic disease you get swelling, pain, immobility (decrease ROM), and contractures
You also get systemic complications and inflammation in the vessels, heart, lungs, kidneys
Rheumatic disease - autoimmune process
The body reacts to its own tissue and treats it as a foreign object and affects all organ systems.
Human Leukocyte Antigen is used as an immune response to help fight off disease.
Rheumatic disease - degenerative process
Inflammation is a secondary process
Degeneration of joints
Rheumatic diseases cause what and affects what
Rheumatic diseases cause immobility and affect muscle, skeletal muscle, ligaments, tendons, cartilage, joint
Rheumatic disease causes fatigue (because the longer you stay in bed and be immobile the weaker your muscles get), organ failure (systemic complications in vessels, heart, lungs, kidneys) and death
Rheumatic disease causes fatigue (because the longer you stay in bed and be immobile the weaker your muscles get), organ failure (systemic complications in vessels, heart, lungs, kidneys) and death
See if the disease is:
Minor vs. life threatening
Primary vs. secondary
Monoarticulate vs. polyarticulate
Inflammatory vs. non inflammatory
Rheumatic disease affects
Hair Skin Eyes Ears Mouth Chest Cardiovascular Abdomen Genetilia Neurological Muscoskeletal And surrounding tissue
Rheumatic diseases are:
Acute (short term)
Insidious (proceed gradually and has harmful effects)
and have Remissions and Exacerbations
List goals for Rheumatic diseases: Decrease inflammation Control pain Increase/maintain mobility and function Increase patient self-knowledge
Rheumatic diseases are:
Acute (short term)
Insidious (proceed gradually and has harmful effects)
and have Remissions and Exacerbations
List goals for rheumatic disease:
Decrease inflammation
Control pain
Increase/maintain mobility and function
Increase patient self-knowledge
RA Affected Systems
Endothelium
Nervous system
Arterial Walls: joints swell and narrow the vessels and weaken them
HDL Production: plaque buildup narrows vessels
RA signs and symptoms
Symmetrical pain and swelling of joints, symptoms not relieved with movement, Sean neck deformity
Stiffness for one hour in AM
Fever/Malaise/Fatigue
Typical starts in small joints and then large joints
Affects joints and spleen and Splenomegaly
RA Diagnosis
Rheumatoid factor (pos) Anti-CCP (pos)
Synovial fluid: yellow, cloudy, leukocytes, complements
RA treatment
Rheumatoid is #1 drug of choice
DMARDs and NSAIDs because dmards takes 1-2 months to work and use nsaids until dmards kick in
Gold salts: z track method and for moderate to severe RA
Prosorba: washing out of plasma
Corticosteroids: lowest dose and shortest time
Rheumatoid arthritis originates in synovial fluid where the fluid thickens and erodes bone and cartilage
Rheumatoid arthritis originates in synovial fluid where the fluid thickens and erodes bone and cartilage
SLE Lupus is more common to occur in who?
African American woman
What is a signature sign of SLE Lupus
Butterfly rash
Ulnar drift (not signature sign but remember it)
SLE Lupus signs and symptoms
Fever, weight loss, pleurisy (difficulty breathing)
SLE Lupus diagnosis
History and Physical Exam and no one test used to diagnose.
Same blood tests as RA
Clinical Manifestations of Epidermis
Cutaneous lesions of the skin, alocepia,
discoid lupid rash
Clinical Manifestations of Muscoskeletal
Polyarthrphagia (pain in multiple joints), stiffness in the AM, swan neck deformity, ulnar drift, arthritis, myovitis, synovitis
Clinical Manifestations of Cardiac
Tachycardia and pericarditis (most common cardiac problem)
Clinical Manifestations of Renal
Hematuria
Proteinuria
Glomerularnephritis
Clinical Manifestations of GI
ab pain
Dysphagia
Menstrual problems
Clinical Manifestations of CNS
They are widespread!!
Seizures
Photosensitivity
Neuropathy
Treatment for SLE Lupus
Acute - control flares so organ damage does not happen
Chronic - monitor to recognize changes in conditions
Medications: corticosteroids, NSAIDs, anti-malarials, immunosuppressants
B cell depleting therapy for severe Lupus
