rheumatology

Question 1

DIP, PIP, 1st CMC, knees, hips, first MTP, cervical/lumbar

Answer 1

OA

Question 2

Cartilage disease

Answer 2

OA

Question 3

OA: DIP/PIP/MCAP/CMC/Wrist?

Answer 3

DIP/PIP/CMC

Question 4

RA: DIP/PIP/MCAP/CMC/Wrist?

Answer 4

PIP/MCP/Wrist

Question 5

OA: Inflam/noninflam

Answer 5

non inflammatory

Question 6

Inflammatory diseases include:

Answer 6

RA, cyrstals, spondyloarthropathies, SLE, vasculitis, polymyositis, dermatomyositis

Question 7

Pseudogout: Synovial fluid is _____?

Answer 7

inflammatory with Ca pyophosphate crystals - rhomboid, birefriengent positive

Question 8

Exercise is good

Answer 8

OA

Question 9

OA: cytokines

Answer 9

IL1, NO, PG, TNFa, IL6, IL17, IL18

Question 10

complement activation, adipokines

Answer 10

OA

Question 11

Symmetric synovitis

Answer 11

RA

Question 12

Shared epitope

Answer 12

RA

Question 13

QKRAA, HLA DR4/1

Answer 13

RA

Question 14

RF IgG immune complex

Answer 14

RA

Question 15

Citrulline - antiCCP ab

Answer 15

Ra

Question 16

Modulation/amplification of local immune response - antigen recognition

Answer 16

RA

Question 17

MSU

Answer 17

Gout

Question 18

Purine

Answer 18

gout

Question 19

Uricase

Answer 19

lacks –> gout

Question 20

Gout cuased by overproductin/underexcretion?

Answer 20

underexcretion

Question 21

Gout Diagnosed

Answer 21

arthrocentesis

Question 22

Needle, negative brefirngent

Answer 22

Grout

Question 23

PPi metabolism from chondrocutes

Answer 23

pseudogout

Question 24

Rhomboid, positive birefringent

Answer 24

pseudogout

Question 25

apolipoprotein B coating inhibits phagocytosis

Answer 25

pseudogout

Question 26

Sacroilitis

Answer 26

spondyloarthropathies

Question 27

Enthesitis

Answer 27

spondyloarthropathies

Question 28

spondyloarthropathies synovium

Answer 28

TNF alpha

Question 29

spondyloarthropathies HLA?

Answer 29

HLA-B27 2%; relative 20%

Question 30

Lower extremity arthritis

Answer 30

reactive arthritis

Question 31

dactylitis

Answer 31

reactive arthritis

Question 32

misdirected recognition of self as foreign

Answer 32

SLE

Question 33

ANtigen driven CD4 T cells

Answer 33

SLE

Question 34

B cell autoreactive stimulation - peripheral abnormalities

Answer 34

SLE

Question 35

polygenic C4A null allele/HLADR3

Answer 35

SLE

Question 36

ANA +

Answer 36

SLE (95%)

Question 37

Ab to platelets

Answer 37

SLE - clotting

Question 38

IMmune complex = immuno floresencents

Answer 38

lumpy bumpy

Question 39

Palpable purpura

Answer 39

vascular permeability

Question 40

antigen driven vascular inflammation

Answer 40

vasculiity

Question 41

cANCA

Answer 41

PR3 - GPA wegners

Question 42

PR3, GPA wegners -- _ ANCA

Answer 42

c

Question 43

pANCA

Answer 43

MPO, microscopic polyangitis MPA

Question 44

MPO, microscopic polyangitis MPA

Answer 44

pANCA

Question 45

intersitial lung disease

Answer 45

PM/DM

Question 46

ANti-aminoacyl tRNA synthetase

Answer 46

cytoplasm

Question 47

Anti-jo-1

Answer 47

antihistadyl tRNA synthease

Question 48

CD8 endomysial distribution

Answer 48

PM

Question 49

CD4 - perivascular

Answer 49

DM

Question 50

Culture of DM/PM

Answer 50

no live cultures can be done