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MSII Unit II > Rock & Roll > Flashcards

Rock & Roll Flashcards

1
Q

Autoimmune diseases such as SLE can cause?

A

Monocytosis

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2
Q

Eosinophilia is >__% of eosinophil?

A

> 7%

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3
Q

Toxic granulation and Dohle bodies in neutrophil indicate?

A

Bacterial sepsis

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4
Q

Lymphocytes with abundant cytoplasma can be from?

A

IM

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5
Q

CD68 is a ___ marker?

A

Macrophages

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6
Q

Lymphoma can be associated with ___?

A

Wiskott-Aldrich syndrome

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7
Q

What is t(8;14) translocation?

A

Burkitt lymphoma

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8
Q

t(14;18)?

A

Follicular lymphoma

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9
Q

t(11;14)?

A

Mantle lymphoma

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10
Q

Only one light chain is expressed in ___?

A

B cell neoplasia

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11
Q

Small lymphocytic lymphoma is associated with?

A

CLL

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12
Q

Involvement of Waldeye ring is commonly associated with?

A

NHL and Diffuse large B cell lymphoma

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13
Q

Can diffuse large B cell lymphoma be cured?

A

Yes

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14
Q

BCL6 gene rearrangement is associated with?

A

Diffuse large B cell lymphoma

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15
Q

Heinz bodies are associated with?

A

G6PD deficiency

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16
Q

t(15;17)?

A

APL, one kind of AML—->cause DIC

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17
Q

Features of myelodysplasia?

A

Can be caused by chemo therapy—>abnormal cell maturation in the marrow—>pancytopenia

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18
Q

PCV can lead to?

A

Myelofibrosis

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19
Q

How does teardrop RBCs come about?

A

Seen when marrow undergoes fibrosis

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20
Q

Leukoerythoblastosis is associated with?

A

Myelophthsic process

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21
Q

Blood loss gives you?

A

Reticulocytosis

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22
Q

Acute respiratory syndrome in SC is due to?

A

RBC sticking to endothelium

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23
Q

Hereiditary spherocytosis is susceptible to parovirus, you wont be able to see any __ in the blood smear?

A

reticulocytes

24
Q

beta thalassemia cause anemia by?

A

alpha chain aggregates lysing RBC in bone marrow—>hemochromatosis

25
SC damaged what organ?
spleen
26
EPO stimulate erythepoesis through?
Inhibition of apoptosis
27
Macrocytic anemia is also called?
megoblastic anemia (B12/folate deficiency)
28
Aplastic anemia shows increase ___ in the bone marrow?
Fat
29
Hereiditary spherocytosis increases risks for ___?
Cholelithiasis (gallstone)
30
What is burr cells and when do you see it?
Echinocytes (moderately spiky cells)--->renal failure
31
What is acanthocytosis and when do you see it?
really spiky cells--->liver failure
32
Myelodysplastic syndrome can be caused by?
chemo
33
Schiling test is for ?
B12 absorption
34
ITP can follow ___ of a child?
viral illness (self-limiting)
35
EBV can cause cold of warm IHA?
Cold
36
TTP is ___ + and cause ___ impairment?
PAS and renal impairment
37
Vasculitis can cause the fragmentation of ?
RBC
38
What cause macroangiopathic hemolytic anemia?
Mechanical sheering like prosthetic valve
39
What kind of genetic pattern is Hemophilia A/B pass from gen to gen?
X-linked
40
Suppurative lymphadenitis drains the site of?
acute bacterial infection
41
CLL can progress to?
Diffuse large B cell lymphoma (Richter transformation)
42
Thymoma is associated with?
Myasthenia gravis
43
Posttransplant lymphoproliferative disorder is often associated with ?
immunsuppression and EBV
44
What is seborrheic keratoses present microscopically?
Pesudocyst/broad anastomosing cords of mature stratified squamous epithelium
45
Dysplastic nevus syndrome/melanoma has mutation in ___ gene?
CDKN2A
46
Reduction of ___ is seen in ichtyosis vulgaris?
reduced keratohyaline granules (thin granulosum)
47
When do you usually see epidermolysis bullosa?
At birth or shortly after (on inflammatory cells nor antibodies)
48
Basophilic epithelial cells is seen in?
Basal cell carcinoma
49
Does HPV warts bleed easily?
Yes
50
Dermatitis herpetiformis presents as?
really itchy hive like vesicles
51
EM is associated with __ reaction?
Drug (immune sensitivity)
52
__ has immune complexes deposited in the endothelial vascular wall?
Cutaneous necrotizing vasculitis
53
Allergic dermatitis sensitization phase and repeated exposure?
Antigen bind to langerhan cells--->langerhand cells travel lymph node and present it to T cells--->reexposure--->langerhand and T cells accumulate--->spongiosis
54
PNH can proceed to?
AML
55
Cold IHA is associated with?
EBV and myco prnumoniae

MSII Unit II (8 decks)

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