Rti Flashcards

(61 cards)

1
Q

What are common organisms causing respiratory tract infections?

A
  • Streptococcus pyogenes (Group A Beta haemolytic)
  • Corynebacterium diphtheriae
  • Bordetella pertussis
  • Staphylococcus aureus
  • Haemophilus influenzae
  • Mycobacterium tuberculosis
  • Streptococcus pneumoniae
  • Klebsiella pneumoniae
  • Respiratory Syncytial Virus
  • Adenovirus
  • Rhinovirus
  • Covid–19 Virus
  • Influenza Virus
  • Parainfluenza Virus
  • Candida albicans
  • Histoplasma capsulatum
  • Paragonimus westermani

This list includes bacteria, viruses, fungi, and parasites responsible for respiratory infections.

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2
Q

What are the common upper respiratory tract infections?

A
  • Common cold / Coryza
  • Covid-19
  • Influenza / Flu
  • Acute tonsillitis
  • Acute pharyngitis (Sore Throat)
  • Acute otitis media
  • Acute sinusitis

URI includes various infections that affect the upper respiratory system.

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3
Q

What are the causative organisms of the common cold?

A
  • Rhinovirus
  • Coronavirus (COVID-19)
  • Respiratory Syncytial Virus

These viruses are prevalent in both adults and children and cause symptoms like fatigue and nasal congestion.

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4
Q

What are the most common symptoms of COVID-19?

A
  • Fever
  • Cough
  • Shortness of breath
  • Weakness
  • Fatigue
  • Nausea
  • Vomiting
  • Diarrhea

COVID-19 can present with a wide range of symptoms beyond respiratory issues.

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5
Q

What is the primary laboratory diagnosis method for COVID-19?

A

PCR / RT PCR testing of nasopharyngeal swab

This method is crucial for identifying the presence of SARS-CoV-2.

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6
Q

What treatment has been shown to decrease mortality in COVID-19 patients?

A

Dexamethasone

Recent trials indicate that dexamethasone can be effective in reducing mortality rates among severe cases.

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7
Q

What preventative measures are recommended for COVID-19?

A
  • Face masks
  • N95 respirators
  • Physical social distancing
  • Hand washing / sanitizer
  • Travel restrictions
  • Isolation of patients
  • Quarantine of exposed people
  • PPE for healthcare workers

These measures are critical in controlling the spread of COVID-19.

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8
Q

What types of vaccines are available for COVID-19?

A
  • RNA Vaccine: Moderna, Pfizer-BioNTech
  • Adenovirus Vector Vaccine: Astra Zeneca / Covishild, Sputnik V
  • Inactivated Virus Vaccine: Covaxin, Sinovac / CoronaVac

Different types of vaccines have been developed to combat COVID-19.

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9
Q

What are the major causes of influenza?

A
  • Influenza virus (80%)
  • Parainfluenza virus (2-9%)
  • Adenovirus (4%)

Influenza can lead to severe respiratory illness and is highly contagious.

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10
Q

What are the features of influenza?

A
  • Sudden onset after 12-24 hours incubation
  • General weakness & fatigue
  • Fever (up to 39-40°C)
  • Severe back, muscle, and joint pain

Influenza symptoms can be severe and occur quickly after exposure.

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11
Q

What is the primary laboratory test for diagnosing influenza?

A

Real time RT PCR

This molecular method detects viral RNA and is crucial for laboratory diagnosis.

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12
Q

What are common causes of acute otitis media?

A
  • Streptococcus pneumoniae (30%)
  • Haemophilus influenzae (20%)
  • Moraxella catarrhalis (15%)
  • Streptococcus pyogenes (3%)
  • Staphylococcus aureus (2%)

These bacteria are responsible for most cases of acute otitis media.

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13
Q

What are the typical symptoms of acute sinusitis?

A
  • Headache
  • Facial congestion
  • Fever
  • Fatigue
  • Nose obstruction
  • Purulent secretions
  • Sensitivity over the sinuses

These symptoms can significantly impact the quality of life.

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14
Q

What is the main treatment for acute sinusitis?

A
  • Amoxicillin
  • Amoxicillin / Clavulonate (Augmentin)
  • Azithromycin

Antibiotics are commonly prescribed for bacterial sinusitis.

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15
Q

What are the common organisms causing tonsillitis and pharyngitis?

A
  • Streptococcus pyogenes
  • Corynebacterium diphtheriae
  • Streptococcus pneumoniae
  • Haemophilus influenzae
  • Staphylococcus aureus
  • Epstein-Barr virus
  • Adenovirus
  • Influenza A, B
  • Respiratory syncytial virus

These pathogens can lead to significant throat infections.

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16
Q

What laboratory test is useful for diagnosing Epstein-Barr Virus (EBV)?

A

Monospot test

This test detects heterophile antibodies indicative of EBV infection.

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17
Q

What is the primary treatment for infectious mononucleosis caused by EBV?

A

Supportive treatment with analgesics

Acyclovir may be used in severe cases.

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18
Q

What are the major causes of lower respiratory tract infections?

A
  • Haemophilus influenzae
  • Streptococcus pneumoniae
  • Staphylococcus aureus
  • Various viruses

Lower respiratory tract infections can be caused by both bacterial and viral pathogens.

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19
Q

What is the incubation period for influenza?

A

18-72 hours

This period is the time from exposure to the onset of symptoms.

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20
Q

What are the features of laryngitis?

A
  • Inflammation of the larynx
  • Often viral
  • Can lead to croup
  • Symptoms include hoarseness and difficulty breathing

Laryngitis can occur in children and may present serious complications.

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21
Q

What is laryngitis?

A

Inflammation of the voice box, or larynx, often viral.

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22
Q

What are the dangerous forms of laryngitis that can occur in children?

A

Croup, Epiglottitis

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23
Q

What is Croup?

A

Breathing difficulty accompanied by a ‘barking’ cough, swelling around the vocal cords, common in infants and children (1-4 years).

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24
Q

What viruses are commonly associated with Croup?

A
  • Parainfluenza viruses (75% of the time) * Influenza viruses * Respiratory syncytial virus (RSV) * Adenovirus
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25
What are the symptoms of Croup?
* A cough that sounds like a seal barking * Labored breathing or stridor * Fever
26
What is the incubation period for parainfluenza viruses?
5-6 days
27
What are the clinical manifestations of parainfluenza virus infections?
* Mild common cold syndrome like rhinitis and pharyngitis * Croup * Pneumonia or Bronchiolitis
28
What is Epiglottitis?
Inflammation & oedema of epiglottis and soft tissue above vocal cords.
29
What age group is primarily affected by Epiglottitis?
Children 2-6 years
30
What are common symptoms of Epiglottitis?
* Fever * Difficulty in breathing due to respiratory obstruction
31
What are the causative organisms of Epiglottitis?
* Haemophilus influenzae * Corynebacterium diphtheriae * Streptococcus pneumoniae
32
What is Bronchitis?
Inflammation of the bronchial tubes.
33
What are the symptoms of acute bronchitis?
* Fever * Dry & painful cough initially * Later cough becomes productive
34
What are some common viruses that cause acute bronchitis?
* Rhinovirus * Parainfluenza virus * Respiratory syncytial virus (RSV) * Influenza virus * Adenovirus
35
What is the treatment for acute bronchitis?
Antibiotics indicated to treat secondary bacterial infection.
36
What is Respiratory Syncytial Virus (RSV)?
A virus that causes bronchiolitis and pneumonia in infants.
37
How is RSV transmitted?
By direct contact or by droplets inhalation.
38
What is the incubation period for RSV?
3-5 days
39
What are the symptoms of RSV infection?
* Running nose * Fever * Wheezing * Dyspnea * Cough
40
What is the laboratory diagnosis method for RSV?
* Antigen detection * Virus isolation * Antibody detection by ELISA
41
What is the drug of choice for treating RSV?
Ribavirin
42
What is the characteristic shape of Adenovirus?
Space vehicle shaped, dsDNA, non-enveloped, icosahedral symmetry.
43
What are the clinical features of pneumonia?
* Fever & chills * Headache * Malaise * Generalized myalgia * Cough
44
What are the common bacterial causes of pneumonia?
* Streptococcus pneumoniae * Staphylococcus aureus * Haemophilus influenzae * Klebsiella pneumoniae
45
What is the standard treatment for Tuberculosis (TB)?
Combination of three or four antibiotics for a period of two months, followed by two antibiotics for a further four months.
46
What are the four-drug combinations commonly used for treating active Pulmonary TB?
* Isoniazid * Rifampicin * Pyrazinamide * Ethambutol
47
What is Whooping cough?
A highly contagious respiratory disease caused by Bordetella pertussis.
48
What is the incubation period for Whooping cough?
10 days
49
What is the characteristic symptom of Whooping cough?
'Whoop' high-pitch sound
50
What is ETHAMBUTOL used for?
It is an antibiotic used primarily in the treatment of tuberculosis. ## Footnote ETHAMBUTOL is one of the first-line drugs for tuberculosis management.
51
What are RIFATER and RIFINAH?
Single tablets containing combinations of drugs: * RIFATER - Rifampicin, Isoniazid, Pyrazinamide * RIFINAH - Rifampicin, Isoniazid ## Footnote These combinations simplify the treatment regimen for patients.
52
What causes whooping cough?
Bordetella pertussis ## Footnote Whooping cough is highly contagious and transmitted through airborne droplets.
53
What is the incubation period for whooping cough?
10 days ## Footnote This period refers to the time between exposure to the bacteria and the onset of symptoms.
54
What vaccine is used to prevent whooping cough?
Triple vaccine - DTP (Diphtheria, Tetanus, Pertussis) ## Footnote Vaccination is crucial for preventing whooping cough in children.
55
What is the appearance of Bordetella pertussis on charcoal blood agar?
Mercury droplet appearance ## Footnote This unique appearance helps in identifying the bacteria in laboratory settings.
56
What type of bacteria is Bordetella pertussis?
Small non-motile, Gram-negative coccobacilli ## Footnote They tend to arrange in loose clumps, giving a characteristic appearance.
57
What are the diagnostic tests for Bordetella pertussis?
Slide agglutination test with specific antisera ## Footnote This test confirms the presence of Bordetella pertussis in patient samples.
58
What are the primary treatments for whooping cough?
Supportive measures and vaccination * Erythromycin * Tetracycline * Chloramphenicol * Ampicillin * Cotrimoxazole ## Footnote Antibiotics are used to reduce the severity and duration of the illness.
59
What symptoms did Amit present with during the clinic visit?
Running nose, cough at night, refusal to drink milk, ear rubbing, and fever ## Footnote These symptoms suggest an upper respiratory tract infection.
60
What did the examination reveal about Amit's eardrum?
Mild redness with no discharge or decreased mobility ## Footnote This finding indicates a possible ear infection but is not definitive.
61
What was the diagnosis for Amit's condition?
Acute upper respiratory tract infection ## Footnote The diagnosis is based on the symptoms and examination findings.