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USMLE Step Uno > Rx Pulm > Flashcards

Rx Pulm Flashcards

1
Q

AAT (alpha1 antitrypsin) deficiency

A

incr elastase activity, loss of elastic fibers, increased compliance, panacinar emphysema.
accumulation of AAT in hepatocytes -> cirrhosis -> incr AST, ALT and decr clotting factors -> elevated PT/INR and PTT

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2
Q

smoking + circular lesion overlying left hilum

A

squamous cell carcinoma -> central bronchogenic carcinoma
secreting PTHrP
decreased phos, hyperCa2+ -> constipation and polyuria (freq. urination)

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USMLE Step Uno (8 decks)

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