Sac 2 regulatory Flashcards
Diffusion
A net movement of substances travelling down its concentration gradient
-high concentration to low concentration
simple diffusion
When molecules directly go through the cell membrane phospholipid bilayer they are usually small molecules or nonpolar eg carbon dioxide and oxygen passive transport=no energy
passive transport
Input energy is not needed (ATP)
osmosis
osmosis is the net movement of water molecules from a solution with a high concentration of water molecules to a solution with a lower concentration of water molecules, through a cell’s partially permeable membrane.
Movement of water through a semipermeable membrane(high concentration to low )
Water molecules can travel through cell membrane or through protein channels in larger quantities
Low water= high solute concentration(eg sugar)
-water loves to move towards solute
excretory system
In mammals, the excretory system is responsible for removing metabolic and other wastes (excess, unnecessary or dangerous materials)from the blood and plays a role in water balance.maintaining homeostasis or internal environmental balance
The Excretory system in consists of organs (skin, the liver, the lungs and the kidney) which are responsible for the elimination of metabolic wastes
what are the Harmful wastes, Nitrogenous wastes such as(n-waste)
ammonia and urea from the metabolism of protein
creatine and creatinine from the metabolic activities of skeletal muscle.
Nephrons purpose
Goal is to process waste products from the blood to create urine (functional unit of a kidney)
Glomerular filtration includes
Glomerular filtration:
Blood pressure forces fluid from the blood in the glomerulus into the bowman’s capsule
The filtrate contains a mixture of glucose, salts, vitamins, nitrogenous wastes and other small molecules
Tubular reabsorption includes
Reabsorption is the process by which water and useful solutes are removed from the filtrate and returned to the blood. The major site of reabsorption is the proximal tubule
When the filtrate exits the glomerulus, it flows into a duct in the nephron called the renal tubule. As it moves, the needed substances and some water are reabsorbed through the tube wall into adjacent capillaries.
move by simple diffusion, facilitated diffusion or active transport(require atp) from the tubule into the surrounding capillaries.
All nutrients, such as glucose and amino acids, and most of the water and inorganic ions, such as sodium, potassium, phosphate and calcium are reabsorbed across the wall of the proximal tubule and enter the peritubular capillaries of the blood stream
Tubular secretion:
Tubular secretion:
Secretion is the process of transporting specific compounds, typically waste products, out of the blood of the peritubular capillaries into the tubular filtrate that will eventually become urine. Secretion occurs mainly in the proximal tubule, but some also occurs in other regions of the tubules
Secretion occurs mainly by active transport, but some also occurs by passive diffusion
substances that are Excreted:
Excess water and solutes such as urea, uric acid ammonia creatinine as well as ions such as sodium and chloride are eliminated in the form of urine.
Urine is transferred out of the kidneys via collecting ducts in the ureters
glomerulus
filters small solutes from the blood
proximal convoluted tubule
reabsorbs ions, water and nutrient removes toxins and adjusts filtrate pH
distal tubule
selectively secretes and absorbs different ions to maintain blood PH balance
collecting duct
reabsorbs solutes and water from the filtrate
loop of henle
Its main function is to reabsorb water and sodium chloride from the filtrate. This conserves water for the organism, producing highly concentrated urine.
Negative Feedback:
Negative Feedback:
A negative feedback loop is a process in which the body senses a change in a variable and activates mechanisms to reverse the change. Negative feedback is a key component of homeostatic control loops that regulate many body variables and maintain the body’s internal conditions within narrow limits.
a stimulus response mechanism where a change in a variable is detected (the stimulus) and a response occurs which reverses the direction of change, bringing the variable back within normal range.
stimulus–response
stimulus–response model a representation of an action that starts with a stimulus and ends with the response to that stimulus
major source of n-waste
urea and ammonium
describe the composition of the filtrate in the bowmans capsule, how is it different to blood plasma
the filtrate leaving the Bowman’s capsule is very similar to blood plasma (filtrate or glomerular filtrate is composed of blood plasma minus plasma protein i.e. it contains all the components of blood plasma except the proteins)
specific substances that are typically reabsorbed by the kidneys
Most of the reabsorption of solutes necessary for normal body function, such as amino acids, glucose, and salts, takes place in the proximal part of the tubule. This reabsorption may be active, as in the case of glucose, amino acids, and peptides, whereas water, chloride, and other ions are passively reabsorbed.
substances being secreted
hydrogen, creatinine, ions, and other types of waste products, such as drugs.
osmoregulation
The process by which an organism regulates the water balance in its body and maintains the homeostasis of the body is called osmoregulation. Osmoregulation is the maintenance of a constant osmotic pressure of the body fluids within a normal range
Controlling water balance is important to ensure the cells of the body are in equilibrium
Too much water outside cells and the cells will absorb it, possibly lysing(the breakdown of a cell caused by damage to its plasma (outer) membrane.)
Too little water inside cells and the cells will release water, possibly collapsing
What is the renal artery afferent and efferent arteriole?
Afferent arterioles deliver blood to the glomerulus, and efferent arterioles carry blood away from the glomerulus.
Afferent: approaching nephron=high oxygen, lower carbon dioxide, high urea, unbalanced ions and water
Efferent: leaving nephron=lower oxygen, higher carbon dioxide, lower urea, balanced ions and water.