salbutamol [Ventolin] Flashcards
1
Q
Classification
Ventolin
A
- bronchodilator
- sympathomimetic
2
Q
INDICATIONs
Ventolin
A
[PCP]
- Bronchospasm
[ACP]
- adjunctive management of hyperkalemia
3
Q
CONTRAINDICATIONs
Ventolin
A
- HYPERSENSITIVITY
- hemodynamically significant tachycardia
4
Q
Dosage - Adult
Ventolin
A
[PCP]
4 x 100 mcg dose via MDI
repeat - PRN
NO MAX dose - assess for signs of toxicity
5
Q
Dosage - Pediatric
Ventolin
A
[PCP]
~~~
< 10kg - NOT INDICATED
10-20kg - 5 x 100mcg
> 20kg 10 x 100mcg
~~~
repeat x 3
6
Q
Pharmacodynamic
Ventolin
A
- Selective β2 stimulation = bronchodilation // vasodilation
- Some β1 effects @ higher doses
- Little or no α stimulation
7
Q
Pharmacokinetics
Ventolin
A
inhaled onset - 5-15mins peak - 60-90mins duration - 3-6hrs
8
Q
Warnings // Precautions
Ventolin
A
- Coronary disease (increased MVO2)
- COPD pts with degenerative heart disease
- Diabetes (decreases the effectiveness of insulin)
9
Q
ADVERSE EFFECTs
Ventolin
A
- restlessness
- apprehension // fear
- weakness
- vertigo
- nausea // vomiting
- tachycardia, dysrhythmias
- sweating // pallor // flushing
- paradoxical worsening of respiratory distress
10
Q
OVERDOSE
Ventolin
A
D/C if repeated doses result in signs of TOXICITY
- HR >150 (>200 in pediatric pts)
- severe tremor
- ventricular dysrhythmias
11
Q
Special Notes
Ventolin
A
- Also a common prescription drug – usual dose by MDI is 100 mcg inhaled per puff
- β2 selectivity is lost with high doses
- 10 mg of Salbutamol may lower serum potassium by as much as 1-1.5 mEq/L (normal K is 3.5-5.0 mEq/L) and is sometimes ordered in the setting of hyperkalemia
