Samplex 2014 Set B Flashcards
(40 cards)
Caseating material in granulomas are mostly derived from:
a. neutrophil
b. macrophage
c. lymphocyte
d. bacilli
B
What is a characteristic tuberculoid leprosy has:
a. Adequate T-cell mediated immunity
b. Adequate B-cell mediated immunity
A
The pseudomembrane of bacillary dysentery is derived from:
a. necrosis of epithelial cell
b. granulomatous reaction
c. exudative material
d. cytoproliferative reaction
C
The enterotoxin that is responsible for illness in cholera is an:
a. endotoxin
b. exotoxin
c. neurotoxin
d. integral part of the cell wall
B
Adult cases of gonorrheal conjunctivitis is transmitted by:
a. sexual intercourse
b. reactivation
c. auto-inoculation
d. mosquitoes
C
Long-term complications of gonococcal salpingitis include:
a. ectopic pregnancy
b. ovarian fibrosis
c. abortion
d. bacteremia
A
Most feared complication of Dengue in the defervescence state.
a. Thrombocytosis
b. Thrombocytopenia
c. Endotoxic Shock
d. Renal Failure
B
Major cause of the common cold:
a. Respiratory Syncitial Virus
b. Coxsackie Virus
c. Rhinovirus
d. Herpes Simplex Virus
C
Salk polio vaccine is composed of
a. formaldehyde inactivated virus
b. attenuated trivalent viral culture
c. combined inactivated and attenuated virus
d. monovalent attenuated virus
A
Associated with squamous cell carcinoma of cervix
a. HPV type 16
b. HPV type 1
c. HSV type 1
d. HSV type 2
A
A classmate in med school developed flu like illness a few days after the start of the sem. A cbcb showed wbc count of 15,000 cells per ml, 55% of which are lymphocytes. A peripheral blood smear has a no. Of atypical forms. IgM antibodies to a certain virus were positive.
Which is the possible causative agent?
a. HSV
b. EBV
c. Dengue
d. HPV2
B
A classmate in med school developed flu like illness a few days after the start of the sem. A cbcb showed wbc count of 15,000 cells per ml, 55% of which are lymphocytes. A peripheral blood smear has a no. Of atypical forms. IgM antibodies to a certain virus were positive.
Of the antibody above, the ff is likely :
a. responsible for clearing the virus from the human body
b. protective to the patient against future infection by the same virus
c. will decrease in titer in a few weeks
d. persist for life
D
Vibrio cholerae adherence and toxin genes are produced by:
A. Plasmids
B. Glycoproteins
C. Salt Concentration
D. Iron Deprivation
D
A 5 y.o. female presents with conjunctivitis, high grade fever, and rinorrhea. Pedia suspects causative agent is a single stranded enveloped RNA of the Paramyxoviridae family.
Transmission of disease is caused by
a. mosquito bite
b. autoinnoculation
c. respiratory droplets
d. intimate contact with case
C
Disease is likely measles
A 5 y.o. female presents with conjunctivitis, high grade fever, and rinorrhea. Pedia suspects causative agent is a single stranded enveloped RNA of the Paramyxoviridae family.
Viremia in this case is
a. persistent
b. transient
c. recurring
d, absent
B
A 5 y.o. female presents with conjunctivitis, high grade fever, and rinorrhea. Pedia suspects causative agent is a single stranded enveloped RNA of the Paramyxoviridae family.
A defective form of the virus
a. nasopharyngeal carcinoma
b. brain tumor
c. subsclerosal panenchepalitis
d. burkitt lymphoma
C
Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder of children and young adults that affects the central nervous system (CNS). It is a slow, but persistent, viral infection caused by defective measles virus-cannot form its envelope.
The single most common abnormality of the dominant oncogenes involves a point mutation of:
a. RAS
b. cFMS
c. cyclin D1
d. RET
A
The most common abnormality in dominant genes in human tumors?
a. RAS
b. cFMS
c. cyclin D1
d. RET
A
Dysregulation of MYC expression resulting from translocation of the MYC gene occurs in:
a) Chronic myelogenous leukemia
b) Neuroblastoma
c) Small cell lung carcinoma
d) Burkitt lymphoma
B
Reduplication of DNA segments producing several copies of proto-oncogenes is exemplified by:
a. C-erb-B2 in breast cancer
b. Bcr-Abl in chronic myelogenous leukemia
c. Rb gene in retinoblastoma
d. Bcl-2 gene in follicular lymphoma
A
An example of an apoptosis gene:
a. RAS
b. n-MYC
c. RB
d. bcl-2
D
Example of a hybrid chromosome:
a. t(8,14)
b. t(14,18)
c. t(9,22)
d. trisomy 21
C
The activation of APC is an example of:
a. signal transduction
b. transcription regulation
c. DNA repair
d. gene amplification
A
Knudson’s hypothesis is associated with:
a. ataxia-telangiectasia
b. Fanconi anemia
c. retinoblastoma
d. Bloom syndrome
C
