Sarcoidosis

Question 1

Findings in Sarcoidosis

Answer 1

1. Erythema nodosum (painful papules), lupus pernio
2. Symetric swelling of knees, PIP,MCP joints
3. Female, young
4. Multi-system involvement, lung most common

Question 2

What is Sarcoidosis

Answer 2

Non caseating granulomas, multi-system
Cause unknown

Question 3

Lofgren syndrome

Answer 3

Sarcoid syndrome
1. Erythema nodosum
2. BHL
3. Arthritis

Question 4

Heerfordt-Waldenstrom Syndrome

Answer 4

Sarcoid syndrome
1. Uveitis
2. Parotid swelling
3. Facial palsy

Question 5

CXR findings, 4 stages of sarcoidosis

Answer 5

1. BHL
2. BHL + PF
3. PF alone
4. Honeycombing fibrosis

Question 6

Vit D, ACE levels increased/decreased in sarcoidosis

Answer 6

Vit D increased causing hypercalcemia
ACE increased - monitoring sarcoidosis

Question 7

Diagnosis of sarcoidosis

Answer 7

CXR … CT… Biopsy
Confirmatory is lung/erythema nodosum skin biopsy showing non-caseating granuloma

Question 8

Spirometry shows which pattern in sarcoidosis

Answer 8

Restrictive
DLCO decreased

Question 9

Rx for hilar lymphadenopathy without lung involvement in sarcoidosis

Answer 9

Not required

Question 10

Rx in sarcoidosis is required in which cases

Answer 10

1. No improvement in 3-6 months
2. Erythema nodosum + arthralgia
3. Eye, CNS or other system involvement
4. Hypercalcemia
5. Symptomatic pulmonary lesions

Question 11

Sarcoidosis is treated with which drug

Answer 11

Corticosteroid