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Flashcards in Sarcoidosis Deck (7)
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What is sarcoidosis

a multisystem disorder of unknown cause characterised by non-caseating granulomas. It is more common in young adults and african people


Features of Sarcoidosis

Acutely -- erythema nodosum, bilateral hilar lymphadenopathy, a 'swinging' fever and polyarthralgia.
Insidious -- dyspnoea, non-productive cough, malaise & weight loss
Can have lupus pernio and hypercalcaemia


Lofgren's Syndromes

an acute form with bilateral hilar lymphadenopathy (BHL), erythema nodosum, fever and polyarthralgia. it usually has an excellent prognosis


Heerfordt's syndrome

Uveoparotid fever - parotid enlargement with fever and uveitis secondary to sarcoidosis


Why does sarcoidosis give you hypercalcaemia?

Macrophages in the granulomas cause increased conversion of Vit D to its active form


Lupus pernio

Chronic, raised and hardened purplish lesion of the skin on face, hands or fingers. resembles frost bite.


Treat with steroids if

Hypercalcaemia, worsening lung function or heart, eye or neurological involvement.