SARS-CoV-2. Flashcards

1
Q

Remdesivir

A

Análogo (nucleósido) de ATP inhibidor de la ARN pol (replicasa)

¿cómo te sientes cuando no tienes ATP?
REMDido = REMDesivir

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2
Q

Molnupiravir

A

Análogo ribonucleósido de la RNA pol (replicasa)

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3
Q

Nirmatrelvir-Ritonavir (Paxlovid)

A

Inhibidor de proteasa Mpro e inhibidor de CYP3A

(Nirmaltrevir es sustrato de CYP3A, por lo que inhibimos con Ritonavir para que logre llegar mayor cantidad de Nirmaltrevir)

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4
Q

SARS-COV2

A

Remdesivir
Molnupiravir
Paxlovid

¿qué le dices al medicamento cuando te enfermas de covid?

“me he REMDido (REMDesivir), MOLdeame (MOLnupiravir) a tu antojo, solo quiero PAZ (PAXlovid)”

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5
Q

Análogo de ATP

A

Remdesivir

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6
Q

Análogo ribonucleósido

A

Molnupiravir

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7
Q

Inhibidor de proteasa e inhibidor de CYP3A:

A

Nirmatrelvir-Ritonavir (Paxlovid)

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8
Q

EA de molnupiravir

A

afecta crecimiento óseo y cartilaginoso, por eso está contraindicado en menores de 18 años

“MOLnUpirAvir MOdULA crecimiento”

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