Schizophrenia Flashcards
(24 cards)
Positive symptoms
Persecutory delusions
Persecutory hallucinations
Thought disorder
Experiences of control
Negative symptoms
Avolition
Flattened affect
Impaired cognitive function; memory
Catatonia
Describe Aneja et al
Case study on early on set schizophrenia
Types of delusions
Persecutory delusion
Grandiose delusion
Delusion of reference
Freeman et al aims (2)
- To find out people with no history of mental illness had thoughts of Persecutory ideation in VR
- Whether there are cognitive or emotional factors that can predict the likelihood of schizo
Freeman sample
12 male 12 female
Avg age 26
UCL; UK
Volunteer sampling
How many avatars in VR
Two and three
BSI describe
53-item
Nine symptom dimensions
Last 7 days
Freeman anxiety measure describe
20 questions
1-4
Gottesman data
Likelihood of developing sch is 1% in gp to 48% in twins
Hilker sample and data
30k twins
Heritability = 79%
Tienari
6.7 % vs 4%
Lindström
Patients w Parkinson’s and high dosage of l-dopa show symptoms like hallucinating
Wise et al
Post mortem studies shows that there were low level of enzymes that broke down dopamine
Nestler
Low levels of dopamine on the prefrontal cortex may be responsible for negative symptom
Frith
-abnormality of self-monitoring
-misinterpretation of perception
-difficulty generating spontaneous actions
Typical antipsychotic
Chlorpromazine
Block dopamine receptors
Atypical antipsychotics
Clozapine
Block dopamine but dissociate rapidly allowing regular transmission
Senksy et al sample
90
16-60 yrs
Diagnosed with treatment resistant schizophrenics
Randomized control trial
Sensky aim
To compare CBT to befriending
Sensky CBT procedure
Discussing emergence
Challenging thoughts
Voice diaries
Created coping strategies
Senksy measures
Comprehensive psyhiatric rating scale CPRS
SANS; scale for assessment of negative symptoms
Drugs that increase dopamine
Amphetamine
Cocaine
Dopamine hypothesis
Identifies a link between excessive amounts of dopamine and positive symptoms
