Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Psychiatry > Schizophrenia > Flashcards

Schizophrenia Flashcards

1
Q

risk ^ 50% by ?

A

childhood viral CNS infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is it assumed that SZP is related to?

A

over activity of dopamine pathways in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

positive symptoms

A

delusions
hallucinations
thought disorder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

negative symptoms

A

apathy
lack of volition (will power)
social withdrawal
cognitive impairment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

1st rank symptoms

A 
passivity phenomena
delusional perception
delusional hallucinations (mainly auditory)
thought interference
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is passivity phenomena

A

belief that they are no longer in control of their own body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Time frame after which SZP can be diagnosed

A

dont diagnose unless symptoms last for >= 6 months and are present much of the time for at least 1m

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

poor prognostic indiactors

A 
male
insidious onset
early onset
cognitive impairment
enlarged ventricles
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Examples of atypical antipsychotics

A

risperidone
olanzapine
quetiapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is more common with the use of atypicals than typicals?

A

metabolic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is better about atypicals

A

less likely to induce EPSE’s

better at tx -ve symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

why do EPSE’s occur

A

antipsychotics block D2 receptors in the nigrostriatum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

examples of typical antipsychotics

HTC

A

chlorpromazine
thioridazine
haloperidol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is acute dystonia

A

muscle spasms
can occur within hours of starting antipsychotics
try procyclidine to treat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

treatment of EPSE’s

A

decrease dose, change to atypical, or try procyclidine (an Ach antagonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

do antipsychotics increase or decrease seizure threshold

A

decrease

17
Q

what is tar dive dyskinesia

A

repetitive involuntary purposeless movements

normally takes years to develop and may be irreversible

18
Q

why can antipsychotics cause hyperprolactinaemia?

A

secretion of prolactin is under inhibitory control by dopamine

19
Q

symptoms of hyperprolactinaemia

A

galactorrhea
amenorrhoea
oligomenorrhoea
infertility

20
Q

treatment of symptomatic hyperprolactinaemia

A

decrease dose or switch to quetiapine (amantadine if not tolerated)

21
Q

how is antipsychotic use related to osteoporosis

A

hyperprolactinaemia > decreased oestrogen and testosterone > osteoporosis

22
Q

what is akathisia and how is it managed

A

s/e of antipsychotics > restlessness

if tx needed > propranolol +/- cyproheptadine

23
Q

which antipsychotics increase the risk of stroke in elderly

A

olanzapine and respiridone

24
Q

what CV effect is common with antipsychotics

A

postural hypotension

25
Q

what are the purposeless movements that can occur with tardive dyskinesia

A

grimacing
sticking tongue out
lip smacking

26
Q

name the antipsychotic that is used ONLY when all others are intolerated

A

clozapine

27
Q

clozapine s/e’s

A

metabolic syndrome and sedation more than any other
hyper salivation
AGRANULOCYTOSIS&raquo_space; FBC even if patient only has a sore throat

28
Q

how is smoking related to clozapine

A

if smoking its fine if it stays constant

but if a patient smokes then stops, they will start metabolising clozapine much faster

29
Q

cardiac problem assoc with clozapine

A

myocarditis

30
Q

clozapine FBC monitoring

A

weekly for 1st 6 months
fortnightly for next 6m
every 4 weeks thereafter
for 1m after cessation

31
Q

examples of acute dystonia

A

torticollis

oculogyric crisis

32
Q

prolonged involuntary upward deviation of the eyes

A

oculogyric crisis

33
Q

‘crick in the neck’

A

torticollis

34
Q

poor prognostic indicators in SZP

A 
low IQ
strong fam hx 
gradual onset
premorbid social withdrawal 
no obvious precipitant

Psychiatry (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions