Flashcards in Schizophrenia and Other Psychotic Disorders Deck (34)
When is the peak onset time for schizophrenia?
-late adolesence and early adulthood
-negative sx have a poor prognosis
+ sx of schizophrenia
-sx added to the presentation
-typically present in the active phase
What is loosening of associations
-when connections among the pts ideas are absent or obscure
-listeners may feel as if understanding of the pts thoughts had been suddenly lost
What does the form of though look like in schizo ppl?
-loosening of associations
-poverty of content and speech
-thoguht blocking: internal interruption in pts speech/thoughts
What does the content of thought llok like in schizo ppl?
-delusions of persecution, reference, influence
-grandiose delusions, somatic delusions
what is the schizo affect like?
Negative sx of schizophrenia
-sx that appear missing from the presentation
-typically present in the residual phase
-anhedonia: they don't have any fun
-poverty of thought
-content of speech
How long do the sx for schizo have to be present?
-6 months!!!!!!***** importante
What are some things we have do be able to rule out when making the dx of schizo?
-street drug use******
psychiatric ddx for schizo
When are ppl with schizo born?
-higher rates in pts born in winter and early spring months
What will schizo eyes look like?
-saccadic eye movements, not smooth when reading over something
What will brain imaging look like in schizo?
-structural volume reduction in cortical structures
-enlarged ventricles (3rd and 4th)
What were some of the big sx that they have to have for most of 1 month?
are schizos more likely to commit homicide?
What is the single leading cause of death in schizos?
What drug to we give suicidal ppl?
-be sure to check for neutropenia
What things do we have to look for in the schizophrenia, Catatonic type?
-motoric immobility as evidenced by catalepsy or stupor
-excessive motor activity (apparently puroposeless and not influenced by external stimuli)
-extreme negativism or mutism
-peculiarities of voluntary movement such as posturing, stereotyped movements, prominent mannerisms or prominent grimacing
-Echolalia or echopraxia
-Benzos for catatonic disorder
What do we have to do pharamcologically for schizo?
-block the DA receptors!!!
-first gen antipsychotics: haloperidol, fluphenazine
-lorazepam calms them down
What are some first generation antipsychotics adverse effects?
-NEuropleptic malignant syndrome
What do the second generation antipsychotics do?
-block DA receptors AND affect serotonin activity
-Clozapine (agranulocytosis... watch out)
-Ziprasidone: QTc prolongation
-Aripiprazole: partial DA agonist
If it ends with "pine", what side effect must we worry about?
What is Schizoaffective disorder?
-Uninterrupted period of illness with either a major depressive episode or manic episode concurrent with sx that meet criterion A for schizophrenia
-Same period of illness, have been delusions or hallucinations for at least 2 weeks in the absence of prominent mood sx
What is brief psychotic disorder?
-Presence of at least ... of the following:
-grossly disorganized or catatonic behavior
-Duration of an episode of the disturbance is at least 1 day and no more than 1 month*****, with eventual return to premorbid level of functioning
What is Schizophreniform?
-Meets criteria A, D, and E for schizophrenia
-an episode of the disorder lasts at least 1 month but less than 6 months
What is delusional disorder?
-delusions of at least 1 month's duration,
-has never met criterion A for schizophrenia
-apart from the impact of the delusion, functioning is not impaired and behavior is not odd or bizarre
If schizo, what time line are we looking for?
-> 6 months